Mango (<i>Mangifera indica</i> L.) Polyphenols: Anti-Inflammatory Intestinal Microbial Health Benefits, and Associated Mechanisms of Actions
Mango is rich in polyphenols including gallotannins and gallic acid, among others. The bioavailability of mango polyphenols, especially polymeric gallotannins, is largely dependent on the intestinal microbiota, where the generation of absorbable metabolites depends on microbial enzymes. Mango polyph...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/26/9/2732 |
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| author | Hyemee Kim Maria Joselyn Castellon-Chicas Shirley Arbizu Stephen T. Talcott Nicholas L. Drury Shayna Smith Susanne U. Mertens-Talcott |
| author_facet | Hyemee Kim Maria Joselyn Castellon-Chicas Shirley Arbizu Stephen T. Talcott Nicholas L. Drury Shayna Smith Susanne U. Mertens-Talcott |
| author_sort | Hyemee Kim |
| collection | DOAJ |
| description | Mango is rich in polyphenols including gallotannins and gallic acid, among others. The bioavailability of mango polyphenols, especially polymeric gallotannins, is largely dependent on the intestinal microbiota, where the generation of absorbable metabolites depends on microbial enzymes. Mango polyphenols can favorably modulate bacteria associated with the production of bioactive gallotannin metabolites including <i>Lactobacillus plantarum</i>, resulting in intestinal health benefits. In several studies, the prebiotic effects of mango polyphenols and dietary fiber, their potential contribution to lower intestinal inflammation and promotion of intestinal integrity have been demonstrated. Additionally, polyphenols occurring in mango have some potential to interact with intestinal and less likely with hepatic enzymes or transporter systems. This review provides an overview of interactions of mango polyphenols with the intestinal microbiome, associated health benefits and underlying mechanisms. |
| first_indexed | 2024-03-10T11:40:05Z |
| format | Article |
| id | doaj.art-0662b0874c4345bbbe7cacdcbea4c154 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T11:40:05Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-0662b0874c4345bbbe7cacdcbea4c1542023-11-21T18:33:42ZengMDPI AGMolecules1420-30492021-05-01269273210.3390/molecules26092732Mango (<i>Mangifera indica</i> L.) Polyphenols: Anti-Inflammatory Intestinal Microbial Health Benefits, and Associated Mechanisms of ActionsHyemee Kim0Maria Joselyn Castellon-Chicas1Shirley Arbizu2Stephen T. Talcott3Nicholas L. Drury4Shayna Smith5Susanne U. Mertens-Talcott6Department of Food Science and Nutrition, Pusan National University, Busan 46241, KoreaDepartment of Food Science and Technology, Texas A&M University, College Station, TX 77843, USADepartment of Food Science and Technology, Texas A&M University, College Station, TX 77843, USADepartment of Food Science and Technology, Texas A&M University, College Station, TX 77843, USADepartment of Food Science and Technology, Texas A&M University, College Station, TX 77843, USADepartment of Food Science and Technology, Texas A&M University, College Station, TX 77843, USADepartment of Food Science and Technology, Texas A&M University, College Station, TX 77843, USAMango is rich in polyphenols including gallotannins and gallic acid, among others. The bioavailability of mango polyphenols, especially polymeric gallotannins, is largely dependent on the intestinal microbiota, where the generation of absorbable metabolites depends on microbial enzymes. Mango polyphenols can favorably modulate bacteria associated with the production of bioactive gallotannin metabolites including <i>Lactobacillus plantarum</i>, resulting in intestinal health benefits. In several studies, the prebiotic effects of mango polyphenols and dietary fiber, their potential contribution to lower intestinal inflammation and promotion of intestinal integrity have been demonstrated. Additionally, polyphenols occurring in mango have some potential to interact with intestinal and less likely with hepatic enzymes or transporter systems. This review provides an overview of interactions of mango polyphenols with the intestinal microbiome, associated health benefits and underlying mechanisms.https://www.mdpi.com/1420-3049/26/9/2732mango polyphenolspolyphenol metabolitesgut healthgut microbiotaintestinal integrityinflammation |
| spellingShingle | Hyemee Kim Maria Joselyn Castellon-Chicas Shirley Arbizu Stephen T. Talcott Nicholas L. Drury Shayna Smith Susanne U. Mertens-Talcott Mango (<i>Mangifera indica</i> L.) Polyphenols: Anti-Inflammatory Intestinal Microbial Health Benefits, and Associated Mechanisms of Actions Molecules mango polyphenols polyphenol metabolites gut health gut microbiota intestinal integrity inflammation |
| title | Mango (<i>Mangifera indica</i> L.) Polyphenols: Anti-Inflammatory Intestinal Microbial Health Benefits, and Associated Mechanisms of Actions |
| title_full | Mango (<i>Mangifera indica</i> L.) Polyphenols: Anti-Inflammatory Intestinal Microbial Health Benefits, and Associated Mechanisms of Actions |
| title_fullStr | Mango (<i>Mangifera indica</i> L.) Polyphenols: Anti-Inflammatory Intestinal Microbial Health Benefits, and Associated Mechanisms of Actions |
| title_full_unstemmed | Mango (<i>Mangifera indica</i> L.) Polyphenols: Anti-Inflammatory Intestinal Microbial Health Benefits, and Associated Mechanisms of Actions |
| title_short | Mango (<i>Mangifera indica</i> L.) Polyphenols: Anti-Inflammatory Intestinal Microbial Health Benefits, and Associated Mechanisms of Actions |
| title_sort | mango i mangifera indica i l polyphenols anti inflammatory intestinal microbial health benefits and associated mechanisms of actions |
| topic | mango polyphenols polyphenol metabolites gut health gut microbiota intestinal integrity inflammation |
| url | https://www.mdpi.com/1420-3049/26/9/2732 |
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