Understanding the Progression of Bone Metastases to Identify Novel Therapeutic Targets

Understanding the Progression of Bone Metastases to Identify Novel Therapeutic Targets

Bone is one of the most preferential target site for cancer metastases, particularly for prostate, breast, kidney, lung and thyroid primary tumours. Indeed, numerous chemical signals and growth factors produced by the bone microenvironment constitute factors promoting cancer cell invasion and aggres...

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Bibliographic Details
Main Authors:	Annie Schmid-Alliana, Heidy Schmid-Antomarchi, Rasha Al-Sahlanee, Patricia Lagadec, Jean-Claude Scimeca, Elise Verron
Format:	Article
Language:	English
Published:	MDPI AG 2018-01-01
Series:	International Journal of Molecular Sciences
Subjects:	bone metastases bone tropism bone microenvironment molecular mechanisms therapeutic strategies
Online Access:	http://www.mdpi.com/1422-0067/19/1/148

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