Classification and treatment strategy for Moyamoya disease-related aneurysms
Abstract Background Moyamoya disease (MMD) is a cerebrovascular disorder characterized by progressive unilateral or bilateral stenosis of the distal internal carotid artery. As hemodynamic features in MMD patients alter, the comorbidity of intracranial aneurysm (IA) is sometimes observed clinically....
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-12-01
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| Series: | Chinese Neurosurgical Journal |
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| Online Access: | https://doi.org/10.1186/s41016-023-00352-1 |
| _version_ | 1797377175840620544 |
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| author | Yangchun Hu Xiaojian Wang Chao Li Liang Zhao Jing Luo Lei Ye Baochun Cheng |
| author_facet | Yangchun Hu Xiaojian Wang Chao Li Liang Zhao Jing Luo Lei Ye Baochun Cheng |
| author_sort | Yangchun Hu |
| collection | DOAJ |
| description | Abstract Background Moyamoya disease (MMD) is a cerebrovascular disorder characterized by progressive unilateral or bilateral stenosis of the distal internal carotid artery. As hemodynamic features in MMD patients alter, the comorbidity of intracranial aneurysm (IA) is sometimes observed clinically. We aim to investigate clinical characteristics and therapeutic strategies for the comorbidity of Moyamoya disease with intracranial aneurysms (MMD-IA). Methods A total of 13 MMD-IA patients were recruited in this study and were manifested to be intracranial hemorrhage. We reviewed the surgical technique notes for all patients. Results According to the locations of an aneurysm, MMD-IA could be divided into several categories: (1) MMD-IA at a circle of Willis—aneurysms usually located at the trunk of Willis circle; (2) MMD-IA at collateral anastomosis—aneurysms located at the distal end of collateral anastomosis; and (3) MMA-IA at basal ganglia region. In this report, aneurysms in 10 patients located at Willis circle, 2 at the pericallosal artery, and 1 at the basal ganglia region. Among them, endovascular embolism was performed among 5 patients. Aneurysm clipping was conducted among 7 patients. A patient with an aneurysm at the basal ganglia region just accepted revascularization treatment. All the treatments were successful. Follow-up studies, ranging from 6 to 24 months, demonstrated all patients received satisfactory curative effects. Conclusion Diverse clinical presentations could be observed among MMD-IA patients. Individualized neurosurgical treatments should be chosen according to the locations of the aneurysm. |
| first_indexed | 2024-03-08T19:48:58Z |
| format | Article |
| id | doaj.art-066bfec1c07e4181b0e07f96b2fb05c3 |
| institution | Directory Open Access Journal |
| issn | 2057-4967 |
| language | English |
| last_indexed | 2024-03-08T19:48:58Z |
| publishDate | 2023-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Chinese Neurosurgical Journal |
| spelling | doaj.art-066bfec1c07e4181b0e07f96b2fb05c32023-12-24T12:10:06ZengBMCChinese Neurosurgical Journal2057-49672023-12-01911710.1186/s41016-023-00352-1Classification and treatment strategy for Moyamoya disease-related aneurysmsYangchun Hu0Xiaojian Wang1Chao Li2Liang Zhao3Jing Luo4Lei Ye5Baochun Cheng6Department of Neurosurgery, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Neurosurgery, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Neurosurgery, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Neurosurgery, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Neurosurgery, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Neurosurgery, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Neurosurgery, The First Affiliated Hospital of Anhui Medical UniversityAbstract Background Moyamoya disease (MMD) is a cerebrovascular disorder characterized by progressive unilateral or bilateral stenosis of the distal internal carotid artery. As hemodynamic features in MMD patients alter, the comorbidity of intracranial aneurysm (IA) is sometimes observed clinically. We aim to investigate clinical characteristics and therapeutic strategies for the comorbidity of Moyamoya disease with intracranial aneurysms (MMD-IA). Methods A total of 13 MMD-IA patients were recruited in this study and were manifested to be intracranial hemorrhage. We reviewed the surgical technique notes for all patients. Results According to the locations of an aneurysm, MMD-IA could be divided into several categories: (1) MMD-IA at a circle of Willis—aneurysms usually located at the trunk of Willis circle; (2) MMD-IA at collateral anastomosis—aneurysms located at the distal end of collateral anastomosis; and (3) MMA-IA at basal ganglia region. In this report, aneurysms in 10 patients located at Willis circle, 2 at the pericallosal artery, and 1 at the basal ganglia region. Among them, endovascular embolism was performed among 5 patients. Aneurysm clipping was conducted among 7 patients. A patient with an aneurysm at the basal ganglia region just accepted revascularization treatment. All the treatments were successful. Follow-up studies, ranging from 6 to 24 months, demonstrated all patients received satisfactory curative effects. Conclusion Diverse clinical presentations could be observed among MMD-IA patients. Individualized neurosurgical treatments should be chosen according to the locations of the aneurysm.https://doi.org/10.1186/s41016-023-00352-1Moyamoya diseaseAneurysmClippingRevascularizationEndovascular embolism |
| spellingShingle | Yangchun Hu Xiaojian Wang Chao Li Liang Zhao Jing Luo Lei Ye Baochun Cheng Classification and treatment strategy for Moyamoya disease-related aneurysms Chinese Neurosurgical Journal Moyamoya disease Aneurysm Clipping Revascularization Endovascular embolism |
| title | Classification and treatment strategy for Moyamoya disease-related aneurysms |
| title_full | Classification and treatment strategy for Moyamoya disease-related aneurysms |
| title_fullStr | Classification and treatment strategy for Moyamoya disease-related aneurysms |
| title_full_unstemmed | Classification and treatment strategy for Moyamoya disease-related aneurysms |
| title_short | Classification and treatment strategy for Moyamoya disease-related aneurysms |
| title_sort | classification and treatment strategy for moyamoya disease related aneurysms |
| topic | Moyamoya disease Aneurysm Clipping Revascularization Endovascular embolism |
| url | https://doi.org/10.1186/s41016-023-00352-1 |
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