Targeted Metabolomics and High-Throughput RNA Sequencing-Based Transcriptomics Reveal Massive Changes in the Streptomyces venezuelae NRRL B-65442 Metabolism Caused by Ethanol Shock

Targeted Metabolomics and High-Throughput RNA Sequencing-Based Transcriptomics Reveal Massive Changes in the Streptomyces venezuelae NRRL B-65442 Metabolism Caused by Ethanol Shock

ABSTRACT The species Streptomyces venezuelae is represented by several distinct strains with variable abilities to biosynthesize structurally diverse secondary metabolites. In this work, we examined the effect of ethanol shock on the transcriptome and metabolome of Streptomyces venezuelae NRRL B-654...

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Bibliographic Details
Main Authors: Olga N. Sekurova, Martin Zehl, Michael Predl, Peter Hunyadi, Thomas Rattei, Sergey B. Zotchev
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
Streptomyces venezuelae
ethanol shock
metabolomics
transcriptomics
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03672-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.03672-22

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