Synthesis and Theoretical Studies of Aromatic Azaborines
Organoboron compounds are well known for their use as synthetic building blocks in several significant reactions, e.g., palladium-catalyzed Suzuki-Miyaura cross-coupling. As an element, boron is fascinating; as part of a molecule it structurally resembles a three-valent atom, but if there is a lone...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Organics |
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| Online Access: | https://www.mdpi.com/2673-401X/3/3/16 |
| _version_ | 1797483842558230528 |
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| author | Pipsa Hirva Petri Turhanen Juri M. Timonen |
| author_facet | Pipsa Hirva Petri Turhanen Juri M. Timonen |
| author_sort | Pipsa Hirva |
| collection | DOAJ |
| description | Organoboron compounds are well known for their use as synthetic building blocks in several significant reactions, e.g., palladium-catalyzed Suzuki-Miyaura cross-coupling. As an element, boron is fascinating; as part of a molecule it structurally resembles a three-valent atom, but if there is a lone pair of electrons nearby, the boron atom’s empty p-orbital may capture the lone pair and form a covalent bond. This is the main aspect that is challenging chemistry during the synthesis of boron containing molecules and may lead into unexpected reactions and products. To study this, we synthesized and studied novel aromatic azaborines for better understanding of their structures and reactions. Here, we report a one-pot method for the synthesis of substituted aromatic azaborines and computational studies of their structure to explain their observed chemical properties. |
| first_indexed | 2024-03-09T22:53:51Z |
| format | Article |
| id | doaj.art-0673854e9b304281871e6157dbc66bbf |
| institution | Directory Open Access Journal |
| issn | 2673-401X |
| language | English |
| last_indexed | 2024-03-09T22:53:51Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Organics |
| spelling | doaj.art-0673854e9b304281871e6157dbc66bbf2023-11-23T18:14:30ZengMDPI AGOrganics2673-401X2022-07-013319620910.3390/org3030016Synthesis and Theoretical Studies of Aromatic AzaborinesPipsa Hirva0Petri Turhanen1Juri M. Timonen2Department of Chemistry, Faculty of Natural Sciences and Forestry, University of Eastern Finland, P.O. Box 111, 80101 Joensuu, FinlandSchool of Pharmacy, Faculty of Health Sciences, Biocenter Kuopio, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, FinlandSchool of Pharmacy, Faculty of Health Sciences, Biocenter Kuopio, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, FinlandOrganoboron compounds are well known for their use as synthetic building blocks in several significant reactions, e.g., palladium-catalyzed Suzuki-Miyaura cross-coupling. As an element, boron is fascinating; as part of a molecule it structurally resembles a three-valent atom, but if there is a lone pair of electrons nearby, the boron atom’s empty p-orbital may capture the lone pair and form a covalent bond. This is the main aspect that is challenging chemistry during the synthesis of boron containing molecules and may lead into unexpected reactions and products. To study this, we synthesized and studied novel aromatic azaborines for better understanding of their structures and reactions. Here, we report a one-pot method for the synthesis of substituted aromatic azaborines and computational studies of their structure to explain their observed chemical properties.https://www.mdpi.com/2673-401X/3/3/16azaborineboron heterocycleB-N heterocycleHorner-Wadsworth-Emmons reactionDFTQTAIM |
| spellingShingle | Pipsa Hirva Petri Turhanen Juri M. Timonen Synthesis and Theoretical Studies of Aromatic Azaborines Organics azaborine boron heterocycle B-N heterocycle Horner-Wadsworth-Emmons reaction DFT QTAIM |
| title | Synthesis and Theoretical Studies of Aromatic Azaborines |
| title_full | Synthesis and Theoretical Studies of Aromatic Azaborines |
| title_fullStr | Synthesis and Theoretical Studies of Aromatic Azaborines |
| title_full_unstemmed | Synthesis and Theoretical Studies of Aromatic Azaborines |
| title_short | Synthesis and Theoretical Studies of Aromatic Azaborines |
| title_sort | synthesis and theoretical studies of aromatic azaborines |
| topic | azaborine boron heterocycle B-N heterocycle Horner-Wadsworth-Emmons reaction DFT QTAIM |
| url | https://www.mdpi.com/2673-401X/3/3/16 |
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