TLR4 promoter rs1927914 variant contributes to the susceptibility of esophageal squamous cell carcinoma in the Chinese population

TLR4 promoter rs1927914 variant contributes to the susceptibility of esophageal squamous cell carcinoma in the Chinese population

Background Toll-like receptor 4 (TLR4), as a key regulator of both innate and acquired immunity, has been linked with the development of various cancers, including esophageal cancer. This study aims to analyze the association of potential functional genetic polymorphisms in TLR4 with the risk of eso...

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Bibliographic Details
Main Authors: Jiaying Li, Hongjiao Wu, Hui Gao, Ruihuan Kou, Yuning Xie, Zhi Zhang, Xuemei Zhang
Format: Article
Language:English
Published: PeerJ Inc. 2021-02-01
Series:PeerJ
Subjects:
TLR4
Esophageal squamous cell carcinoma
Single nucleotide polymorphism
Innate immune
Online Access:https://peerj.com/articles/10754.pdf

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