The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle.

The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle.

Mycobacterium tuberculosis (Mtb) resides in a long-lived phagosomal compartment that resists maturation. The manner by which Mtb antigens are processed and presented on MHC Class I molecules is poorly understood. Using human dendritic cells and IFN-gamma release by CD8(+) T cell clones, we examined...

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Bibliographic Details
Main Authors: Jeff E Grotzke, Melanie J Harriff, Anne C Siler, Dawn Nolt, Jacob Delepine, Deborah A Lewinsohn, David M Lewinsohn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2661020?pdf=render

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