UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma

UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma

Abstract Background Ubiquitin-conjugating enzyme E2T (UBE2T) acts as an oncogene in various types of cancer. However, the mechanisms behind its oncogenic role remain unclear in lung cancer. This study aims to explore the function and clinical relevance of UBE2T in lung cancer. Methods Lentiviral vec...

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Bibliographic Details
Main Authors: Jinhong Zhu, Haijiao Ao, Mingdong Liu, Kui Cao, Jianqun Ma
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Journal of Translational Medicine
Subjects:
UBE2T
Lung cancer
p53
Autophagy
Prognostic signature
Online Access:https://doi.org/10.1186/s12967-021-03056-1

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