Experimental evolution of an RNA virus in wild birds: evidence for host-dependent impacts on population structure and competitive fitness.
Within hosts, RNA viruses form populations that are genetically and phenotypically complex. Heterogeneity in RNA virus genomes arises due to error-prone replication and is reduced by stochastic and selective mechanisms that are incompletely understood. Defining how natural selection shapes RNA virus...
Main Authors: | Nathan D Grubaugh, Darci R Smith, Doug E Brackney, Angela M Bosco-Lauth, Joseph R Fauver, Corey L Campbell, Todd A Felix, Hannah Romo, Nisha K Duggal, Elizabeth A Dietrich, Tyler Eike, Jennifer E Beane, Richard A Bowen, William C Black, Aaron C Brault, Gregory D Ebel |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-05-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4439088?pdf=render |
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