Comparative Study of Two Tenecteplase Therapeutic Protein Purification Methods

Therapeutic Tenecteplase (TNKase) is a recombinant and site directed mutant version of human tissue plasminogen activator (TPA) with clinical advantages over TPA. Due to specific glycosylation, TNKase is preferred to over-express in mammalian cell lines such as Chinese Hamster Ovarian (CHO) Cells. T...

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Bibliographic Details
Main Author: Hossein Javid
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2021-09-01
Series:Trends in Pharmaceutical Sciences
Subjects:
Online Access:https://tips.sums.ac.ir/article_47722_efe5fa2e3e5a9dd64737d26fb46cd3f7.pdf