Spindle checkpoint activation by fungal orthologs of the S. cerevisiae Mps1 kinase.
There is an ongoing need for antifungal agents to treat humans. Identification of new antifungal agents can be based on screening compounds using whole cell assays. Screening compounds that target a particular molecule is possible in budding yeast wherein sophisticated strain engineering allows for...
Main Authors: | Amy Fabritius, Anabel Alonso, Andrew Wood, Shaheen Sulthana, Mark Winey |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2024-01-01
|
Series: | PLoS ONE |
Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0301084&type=printable |
Similar Items
-
Spindle checkpoint activation by fungal orthologs of the S. cerevisiae Mps1 kinase
by: Amy Fabritius, et al.
Published: (2024-01-01) -
Chromosomal instability and tumorigenesis : genetic analysis of the murine spindle checkpoint gene Mps1
by: Xie, Stephanie Zhi-Juan
Published: (2007) -
Interactions between N-terminal Modules in MPS1 Enable Spindle Checkpoint Silencing
by: Spyridon T. Pachis, et al.
Published: (2019-02-01) -
Plk1 and Mps1 Cooperatively Regulate the Spindle Assembly Checkpoint in Human Cells
by: Conrad von Schubert, et al.
Published: (2015-07-01) -
Protein Phosphatase 1 inactivates Mps1 to ensure efficient Spindle Assembly Checkpoint silencing
by: Margarida Moura, et al.
Published: (2017-05-01)