Variability of Steroid Prescription for COVID-19 Associated Pneumonia in Real-Life, Non-Trial Settings
The RECOVERY study documented lower 28-day mortality with the use of dexamethasone in hospitalized patients on invasive mechanical ventilation or oxygen with COVID-19 Pneumonia. We aimed to examine the practice patterns of steroids use, and their impact on mortality and length of stay in ICU. We ret...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2022-11-01
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| Series: | The Journal of Critical Care Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/jccm-2022-0025 |
| _version_ | 1797427035104083968 |
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| author | Nadeem Rashid Bon Islam Algohary Doaa Kafeel Khan Mohd Gundawar Nilesh Abdullah Mohammed Sharma Ekta Galal Elzeiny Moatz Mahmoud Mayada Elhoufi Ashraf Alshaikh Sayed Ahmed Yusra Omar Gheno Gloria Salama Khalil Maged Talaat Hussain Tamseela |
| author_facet | Nadeem Rashid Bon Islam Algohary Doaa Kafeel Khan Mohd Gundawar Nilesh Abdullah Mohammed Sharma Ekta Galal Elzeiny Moatz Mahmoud Mayada Elhoufi Ashraf Alshaikh Sayed Ahmed Yusra Omar Gheno Gloria Salama Khalil Maged Talaat Hussain Tamseela |
| author_sort | Nadeem Rashid |
| collection | DOAJ |
| description | The RECOVERY study documented lower 28-day mortality with the use of dexamethasone in hospitalized patients on invasive mechanical ventilation or oxygen with COVID-19 Pneumonia. We aimed to examine the practice patterns of steroids use, and their impact on mortality and length of stay in ICU. We retrospectively examined records of all patients with confirmed Covid 19 pneumonia admitted to the ICU of Dubai hospital from January 1st, 2020 – June 30th, 2020. We assigned patients to four groups (No steroids, low dose, medium dose, and high dose steroids). The primary clinical variable of interest was doses of steroids. Secondary outcomes were 28-day mortality and length of stay in ICU”. We found variability in doses of steroid treatment. The most frequently used dose was the high dose. Patients who survived were on significantly higher doses of steroids and had significantly longer stays in ICU. The prescription of steroids in Covid-19 ARDS is variable. The dose of steroids impacts mortality rate and length of stay in ICU, although patients treated with high dose steroids seem to stay more days in ICU. |
| first_indexed | 2024-03-09T08:38:27Z |
| format | Article |
| id | doaj.art-068aab1e94a9499ba635d47ae5227dee |
| institution | Directory Open Access Journal |
| issn | 2393-1817 |
| language | English |
| last_indexed | 2024-03-09T08:38:27Z |
| publishDate | 2022-11-01 |
| publisher | Sciendo |
| record_format | Article |
| series | The Journal of Critical Care Medicine |
| spelling | doaj.art-068aab1e94a9499ba635d47ae5227dee2023-12-02T17:28:05ZengSciendoThe Journal of Critical Care Medicine2393-18172022-11-018425926510.2478/jccm-2022-0025Variability of Steroid Prescription for COVID-19 Associated Pneumonia in Real-Life, Non-Trial SettingsNadeem Rashid0Bon Islam1Algohary Doaa2Kafeel Khan Mohd3Gundawar Nilesh4Abdullah Mohammed5Sharma Ekta6Galal Elzeiny Moatz7Mahmoud Mayada8Elhoufi Ashraf9Alshaikh Sayed Ahmed Yusra Omar10Gheno Gloria11Salama Khalil Maged Talaat12Hussain Tamseela13Dubai Hospital, Dubai, UAE, United Arab EmiratesDubai Hospital, Dubai, UAE, United Arab EmiratesDubai Hospital, Dubai, UAE, United Arab EmiratesDubai Hospital, Dubai, UAE, United Arab EmiratesDubai Hospital, Dubai, UAE, United Arab EmiratesDubai Hospital, Dubai, UAE, United Arab EmiratesDubai Hospital, Dubai, UAE, United Arab EmiratesDubai Hospital, Dubai, UAE, United Arab EmiratesDubai Hospital, Dubai, UAE, United Arab EmiratesDubai Hospital, Dubai, UAE, United Arab EmiratesDubai Hospital, Dubai, UAE, United Arab EmiratesRonin Institute for Independent Scholarship, Montclair, New Jersey, USADubai Hospital, Dubai, UAE, United Arab EmiratesRonin Institute for Independent Scholarship, Montclair, New Jersey, USAThe RECOVERY study documented lower 28-day mortality with the use of dexamethasone in hospitalized patients on invasive mechanical ventilation or oxygen with COVID-19 Pneumonia. We aimed to examine the practice patterns of steroids use, and their impact on mortality and length of stay in ICU. We retrospectively examined records of all patients with confirmed Covid 19 pneumonia admitted to the ICU of Dubai hospital from January 1st, 2020 – June 30th, 2020. We assigned patients to four groups (No steroids, low dose, medium dose, and high dose steroids). The primary clinical variable of interest was doses of steroids. Secondary outcomes were 28-day mortality and length of stay in ICU”. We found variability in doses of steroid treatment. The most frequently used dose was the high dose. Patients who survived were on significantly higher doses of steroids and had significantly longer stays in ICU. The prescription of steroids in Covid-19 ARDS is variable. The dose of steroids impacts mortality rate and length of stay in ICU, although patients treated with high dose steroids seem to stay more days in ICU.https://doi.org/10.2478/jccm-2022-0025covid-19infectionsteroidsards |
| spellingShingle | Nadeem Rashid Bon Islam Algohary Doaa Kafeel Khan Mohd Gundawar Nilesh Abdullah Mohammed Sharma Ekta Galal Elzeiny Moatz Mahmoud Mayada Elhoufi Ashraf Alshaikh Sayed Ahmed Yusra Omar Gheno Gloria Salama Khalil Maged Talaat Hussain Tamseela Variability of Steroid Prescription for COVID-19 Associated Pneumonia in Real-Life, Non-Trial Settings The Journal of Critical Care Medicine covid-19 infection steroids ards |
| title | Variability of Steroid Prescription for COVID-19 Associated Pneumonia in Real-Life, Non-Trial Settings |
| title_full | Variability of Steroid Prescription for COVID-19 Associated Pneumonia in Real-Life, Non-Trial Settings |
| title_fullStr | Variability of Steroid Prescription for COVID-19 Associated Pneumonia in Real-Life, Non-Trial Settings |
| title_full_unstemmed | Variability of Steroid Prescription for COVID-19 Associated Pneumonia in Real-Life, Non-Trial Settings |
| title_short | Variability of Steroid Prescription for COVID-19 Associated Pneumonia in Real-Life, Non-Trial Settings |
| title_sort | variability of steroid prescription for covid 19 associated pneumonia in real life non trial settings |
| topic | covid-19 infection steroids ards |
| url | https://doi.org/10.2478/jccm-2022-0025 |
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