Poly(<i>N</i>-vinylcaprolactam) and Salicylic Acid Polymeric Prodrug Grafted onto Medical Silicone to Obtain a Novel Thermo- and pH-Responsive Drug Delivery System for Potential Medical Devices

Poly(<i>N</i>-vinylcaprolactam) and Salicylic Acid Polymeric Prodrug Grafted onto Medical Silicone to Obtain a Novel Thermo- and pH-Responsive Drug Delivery System for Potential Medical Devices

New medical devices with anti-inflammatory properties are critical to prevent inflammatory processes and infections in medical/surgical procedures. In this work, we present a novel functionalization of silicone for medical use with a polymeric prodrug and a thermosensitive polymer, by graft polymeri...

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Bibliographic Details
Main Authors: José M. Cornejo-Bravo, Kenia Palomino, Giovanni Palomino-Vizcaino, Oscar M. Pérez-Landeros, Mario Curiel-Alvarez, Benjamín Valdez-Salas, Emilio Bucio, Héctor Magaña
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Materials
Subjects:
medical devices
thermo-/pH sensitivity
graft copolymerization
polymeric prodrug
drug delivery
medical/surgical procedures
Online Access:https://www.mdpi.com/1996-1944/14/5/1065

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