High prevalence of vitamin D deficiency in children and adolescents with type 1 diabetes
Background: Vitamin D is important for bone health. An inadequate supply of vitamin D to the body is associated with a higher fracture risk in the elderly. Young adults with type 1 diabetes are reported to have a lower peak bone mass than healthy individuals, which could possibly lead to an incre...
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| Format: | Article |
| Language: | English |
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SMW supporting association (Trägerverein Swiss Medical Weekly SMW)
2010-08-01
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| Series: | Swiss Medical Weekly |
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| Online Access: | https://www.smw.ch/index.php/smw/article/view/1176 |
| _version_ | 1797979575713529856 |
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| author | M Janner P Ballinari PE Mullis CE Flück |
| author_facet | M Janner P Ballinari PE Mullis CE Flück |
| author_sort | M Janner |
| collection | DOAJ |
| description |
Background: Vitamin D is important for bone health. An inadequate supply of vitamin D to the body is associated with a higher fracture risk in the elderly. Young adults with type 1 diabetes are reported to have a lower peak bone mass than healthy individuals, which could possibly lead to an increased fracture risk in the future. The prevalence of vitamin D deficiency in healthy young people is high. Thus, optimal supply of vitamin D may be of particular importance for bone health in children with type 1 diabetes.
Methods: In this prospective cross-sectional study we measured serum 25-hydroxy-vitamin D, iPTH, total and ionised calcium, phosphate, and alkaline phosphatase in 129 Swiss children and adolescents with type 1 diabetes.
Results: Of the 129 subjects 78 (60.5%) were vitamin D deficient, defined as a 25-hydroxy-vitamin-D level below 50 nmol/L. During the winter this number rose to 84.1%. 25-hydroxy-vitamin-D levels showed marked seasonal fluctuations, whereas there was no correlation with diabetes control. Despite the high prevalence of vitamin D deficiency, we found a low prevalence of secondary hyperparathyroidism in vitamin D deficient diabetic children and adolescents.
Conclusions:Prevalence of vitamin D deficiency in diabetic children and adolescents is high. Therefore, screening for vitamin D deficiency and supplementation in children with low vitamin D levels may be considered.
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| first_indexed | 2024-04-11T05:41:59Z |
| format | Article |
| id | doaj.art-068b856c329b4b1bae4b20678ba72f23 |
| institution | Directory Open Access Journal |
| issn | 1424-3997 |
| language | English |
| last_indexed | 2024-04-11T05:41:59Z |
| publishDate | 2010-08-01 |
| publisher | SMW supporting association (Trägerverein Swiss Medical Weekly SMW) |
| record_format | Article |
| series | Swiss Medical Weekly |
| spelling | doaj.art-068b856c329b4b1bae4b20678ba72f232022-12-22T04:42:31ZengSMW supporting association (Trägerverein Swiss Medical Weekly SMW)Swiss Medical Weekly1424-39972010-08-01140353610.4414/smw.2010.13091High prevalence of vitamin D deficiency in children and adolescents with type 1 diabetesM JannerP BallinariPE MullisCE Flück Background: Vitamin D is important for bone health. An inadequate supply of vitamin D to the body is associated with a higher fracture risk in the elderly. Young adults with type 1 diabetes are reported to have a lower peak bone mass than healthy individuals, which could possibly lead to an increased fracture risk in the future. The prevalence of vitamin D deficiency in healthy young people is high. Thus, optimal supply of vitamin D may be of particular importance for bone health in children with type 1 diabetes. Methods: In this prospective cross-sectional study we measured serum 25-hydroxy-vitamin D, iPTH, total and ionised calcium, phosphate, and alkaline phosphatase in 129 Swiss children and adolescents with type 1 diabetes. Results: Of the 129 subjects 78 (60.5%) were vitamin D deficient, defined as a 25-hydroxy-vitamin-D level below 50 nmol/L. During the winter this number rose to 84.1%. 25-hydroxy-vitamin-D levels showed marked seasonal fluctuations, whereas there was no correlation with diabetes control. Despite the high prevalence of vitamin D deficiency, we found a low prevalence of secondary hyperparathyroidism in vitamin D deficient diabetic children and adolescents. Conclusions:Prevalence of vitamin D deficiency in diabetic children and adolescents is high. Therefore, screening for vitamin D deficiency and supplementation in children with low vitamin D levels may be considered. https://www.smw.ch/index.php/smw/article/view/117625-OH-cholecalciferolparathyroid hormonetype 1 diabetesvitamin D deficiency |
| spellingShingle | M Janner P Ballinari PE Mullis CE Flück High prevalence of vitamin D deficiency in children and adolescents with type 1 diabetes Swiss Medical Weekly 25-OH-cholecalciferol parathyroid hormone type 1 diabetes vitamin D deficiency |
| title | High prevalence of vitamin D deficiency in children and adolescents with type 1 diabetes |
| title_full | High prevalence of vitamin D deficiency in children and adolescents with type 1 diabetes |
| title_fullStr | High prevalence of vitamin D deficiency in children and adolescents with type 1 diabetes |
| title_full_unstemmed | High prevalence of vitamin D deficiency in children and adolescents with type 1 diabetes |
| title_short | High prevalence of vitamin D deficiency in children and adolescents with type 1 diabetes |
| title_sort | high prevalence of vitamin d deficiency in children and adolescents with type 1 diabetes |
| topic | 25-OH-cholecalciferol parathyroid hormone type 1 diabetes vitamin D deficiency |
| url | https://www.smw.ch/index.php/smw/article/view/1176 |
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