Periodontal Disease and Vitamin D Deficiency in Pregnant Women: Which Correlation with Preterm and Low-Weight Birth?
Periodontal disease seems to be correlated with low vitamin D serum levels, preterm birth (PTB) and low birth weight (LBW), although the literature still lacks a consensus. This study aimed to investigate this correlation in a cohort of pregnant women over 20 weeks of gestation from the University H...
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MDPI AG
2021-10-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/19/4578 |
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| author | Martina Ferrillo Mario Migliario Andrea Roccuzzo Pedro Molinero-Mourelle Giovanni Falcicchio Giuseppina Rosaria Umano Federica Pezzotti Pier Luigi Foglio Bonda Dario Calafiore Alessandro de Sire |
| author_facet | Martina Ferrillo Mario Migliario Andrea Roccuzzo Pedro Molinero-Mourelle Giovanni Falcicchio Giuseppina Rosaria Umano Federica Pezzotti Pier Luigi Foglio Bonda Dario Calafiore Alessandro de Sire |
| author_sort | Martina Ferrillo |
| collection | DOAJ |
| description | Periodontal disease seems to be correlated with low vitamin D serum levels, preterm birth (PTB) and low birth weight (LBW), although the literature still lacks a consensus. This study aimed to investigate this correlation in a cohort of pregnant women over 20 weeks of gestation from the University Hospital “Maggiore della Carità”, Novara, Italy. We assessed serum levels of vitamin D and oral health status through the following indexes: Oral Hygiene Index (OHI), Plaque Control Record (PCR), Gingival Bleeding Index (GBI), and Community Periodontal Index of Treatment Needs (CPTIN). Moreover, we assessed the number of PTB and LBW among the newborns. Out of 121 pregnant women recruited, 72 (mean age 29.91 ± 3.64 years) were included. There was a statistically significant correlation between preterm and OHI > 3 (<i>p</i> = 0.033), and between LBW and OHI > 3 (<i>p</i> = 0.005) and CPITN = 3 (<i>p</i> = 0.027). Both pregnant women with vitamin D deficiency ((25-hydroxy-vitamin D) < 30 ng/mL) and PTB plus LBW newborns were significantly correlated (<i>p</i> < 0.05) with poor levels of all oral health status indexes during pregnancy. Furthermore, these conditions (women with hypovitaminosis D and combination of PTB and LBW) were shown to be significantly correlated (<i>p</i> < 0.001). Taken together, our findings reported a high prevalence of PTB and LBW with poor oral health and vitamin D deficiency in pregnant women. |
| first_indexed | 2024-03-10T06:56:35Z |
| format | Article |
| id | doaj.art-068c189b189f4ec9b9f1ec0047e9c116 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T06:56:35Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-068c189b189f4ec9b9f1ec0047e9c1162023-11-22T16:21:33ZengMDPI AGJournal of Clinical Medicine2077-03832021-10-011019457810.3390/jcm10194578Periodontal Disease and Vitamin D Deficiency in Pregnant Women: Which Correlation with Preterm and Low-Weight Birth?Martina Ferrillo0Mario Migliario1Andrea Roccuzzo2Pedro Molinero-Mourelle3Giovanni Falcicchio4Giuseppina Rosaria Umano5Federica Pezzotti6Pier Luigi Foglio Bonda7Dario Calafiore8Alessandro de Sire9Department of Surgical Sciences, Dental School, University of Turin, 10126 Turin, ItalyDepartment of Translational Medicine, University of Eastern Piedmont, 28100 Novara, ItalyDepartment of Periodontology, School of Dental Medicine, University of Bern, 3010 Bern, SwitzerlandDepartment of Reconstructive Dentistry and Gerodontology, School of Dental Medicine, University of Bern, Freiburgstrasse 7, 3010 Bern, SwitzerlandDepartment of Biomedical Science and Human Oncology, University of Bari “Aldo Moro”, 70124 Bari, ItalyDepartment of Woman, Child and of General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyDental Clinic, University Hospital “Maggiore della Carità”, 28100 Novara, ItalyDepartment of Translational Medicine, University of Eastern Piedmont, 28100 Novara, ItalyDepartment of Neurosciences, ASST Carlo Poma, 46100 Mantova, ItalyDepartment of Medical and Surgical Sciences, University of Catanzaro “Magna Graecia”, 88100 Catanzaro, ItalyPeriodontal disease seems to be correlated with low vitamin D serum levels, preterm birth (PTB) and low birth weight (LBW), although the literature still lacks a consensus. This study aimed to investigate this correlation in a cohort of pregnant women over 20 weeks of gestation from the University Hospital “Maggiore della Carità”, Novara, Italy. We assessed serum levels of vitamin D and oral health status through the following indexes: Oral Hygiene Index (OHI), Plaque Control Record (PCR), Gingival Bleeding Index (GBI), and Community Periodontal Index of Treatment Needs (CPTIN). Moreover, we assessed the number of PTB and LBW among the newborns. Out of 121 pregnant women recruited, 72 (mean age 29.91 ± 3.64 years) were included. There was a statistically significant correlation between preterm and OHI > 3 (<i>p</i> = 0.033), and between LBW and OHI > 3 (<i>p</i> = 0.005) and CPITN = 3 (<i>p</i> = 0.027). Both pregnant women with vitamin D deficiency ((25-hydroxy-vitamin D) < 30 ng/mL) and PTB plus LBW newborns were significantly correlated (<i>p</i> < 0.05) with poor levels of all oral health status indexes during pregnancy. Furthermore, these conditions (women with hypovitaminosis D and combination of PTB and LBW) were shown to be significantly correlated (<i>p</i> < 0.001). Taken together, our findings reported a high prevalence of PTB and LBW with poor oral health and vitamin D deficiency in pregnant women.https://www.mdpi.com/2077-0383/10/19/4578periodontal diseaseoral hygienevitamin Dvitamin D deficiencypreterm birthlow birth weight |
| spellingShingle | Martina Ferrillo Mario Migliario Andrea Roccuzzo Pedro Molinero-Mourelle Giovanni Falcicchio Giuseppina Rosaria Umano Federica Pezzotti Pier Luigi Foglio Bonda Dario Calafiore Alessandro de Sire Periodontal Disease and Vitamin D Deficiency in Pregnant Women: Which Correlation with Preterm and Low-Weight Birth? Journal of Clinical Medicine periodontal disease oral hygiene vitamin D vitamin D deficiency preterm birth low birth weight |
| title | Periodontal Disease and Vitamin D Deficiency in Pregnant Women: Which Correlation with Preterm and Low-Weight Birth? |
| title_full | Periodontal Disease and Vitamin D Deficiency in Pregnant Women: Which Correlation with Preterm and Low-Weight Birth? |
| title_fullStr | Periodontal Disease and Vitamin D Deficiency in Pregnant Women: Which Correlation with Preterm and Low-Weight Birth? |
| title_full_unstemmed | Periodontal Disease and Vitamin D Deficiency in Pregnant Women: Which Correlation with Preterm and Low-Weight Birth? |
| title_short | Periodontal Disease and Vitamin D Deficiency in Pregnant Women: Which Correlation with Preterm and Low-Weight Birth? |
| title_sort | periodontal disease and vitamin d deficiency in pregnant women which correlation with preterm and low weight birth |
| topic | periodontal disease oral hygiene vitamin D vitamin D deficiency preterm birth low birth weight |
| url | https://www.mdpi.com/2077-0383/10/19/4578 |
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