DeconPeaker, a Deconvolution Model to Identify Cell Types Based on Chromatin Accessibility in ATAC-Seq Data of Mixture Samples
While our understanding of cellular and molecular processes has grown exponentially, issues related to the cell microenvironment and cellular heterogeneity have sparked a new debate concerning the cell identity. Cell composition (chromatin and nuclear architecture) poses a strong risk for dynamic ch...
Main Authors: | Huamei Li, Amit Sharma, Kun Luo, Zhaohui S. Qin, Xiao Sun, Hongde Liu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-06-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fgene.2020.00392/full |
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