Global prevalence of Cryptosporidium spp. in pigs: a systematic review and meta-analysis
Cryptosporidium spp. are significant opportunistic pathogens causing diarrhoea in humans and animals. Pigs are one of the most important potential hosts for Cryptosporidium. We evaluated the prevalence of Cryptosporidium in pigs globally using published information and a random-effects model. In tot...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2023-05-01
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| Series: | Parasitology |
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| Online Access: | https://www.cambridge.org/core/product/identifier/S0031182023000276/type/journal_article |
| _version_ | 1797775937471774720 |
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| author | Yuancai Chen Huikai Qin Yayun Wu Huiyan Xu Jianying Huang Junqiang Li Longxian Zhang |
| author_facet | Yuancai Chen Huikai Qin Yayun Wu Huiyan Xu Jianying Huang Junqiang Li Longxian Zhang |
| author_sort | Yuancai Chen |
| collection | DOAJ |
| description | Cryptosporidium spp. are significant opportunistic pathogens causing diarrhoea in humans and animals. Pigs are one of the most important potential hosts for Cryptosporidium. We evaluated the prevalence of Cryptosporidium in pigs globally using published information and a random-effects model. In total, 131 datasets from 36 countries were included in the final quantitative analysis. The global prevalence of Cryptosporidium in pigs was 16.3% (8560/64 809; 95% confidence interval [CI] 15.0–17.6%). The highest prevalence of Cryptosporidium in pigs was 40.8% (478/1271) in Africa. Post-weaned pigs had a significantly higher prevalence (25.8%; 2739/11 824) than pre-weaned, fattening and adult pigs. The prevalence of Cryptosporidium was higher in pigs with no diarrhoea (12.2%; 371/3501) than in pigs that had diarrhoea (8.0%; 348/4874). Seven Cryptosporidium species (Cryptosporidium scrofarum, Cryptosporidium suis, Cryptosporidium parvum, Cryptosporidium muris, Cryptosporidium tyzzeri, Cryptosporidium andersoni and Cryptosporidium struthioni) were detected in pigs globally. The proportion of C. scrofarum was 34.3% (1491/4351); the proportion of C. suis was 31.8% (1385/4351) and the proportion of C. parvum was 2.3% (98/4351). The influence of different geographic factors (latitude, longitude, mean yearly temperature, mean yearly relative humidity and mean yearly precipitation) on the infection rate of Cryptosporidium in pigs was also analysed. The results indicate that C. suis is the dominant species in pre-weaned pigs, while C. scrofarum is the dominant species in fattening and adult pigs. The findings highlight the role of pigs as possible potential hosts of zoonotic cryptosporidiosis and the need for additional studies on the prevalence, transmission and control of Cryptosporidium in pigs. |
| first_indexed | 2024-03-12T22:43:50Z |
| format | Article |
| id | doaj.art-06927004afee49d98f63f97f5b5e980a |
| institution | Directory Open Access Journal |
| issn | 0031-1820 1469-8161 |
| language | English |
| last_indexed | 2024-03-12T22:43:50Z |
| publishDate | 2023-05-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Parasitology |
| spelling | doaj.art-06927004afee49d98f63f97f5b5e980a2023-07-21T09:25:20ZengCambridge University PressParasitology0031-18201469-81612023-05-0115053154410.1017/S0031182023000276Global prevalence of Cryptosporidium spp. in pigs: a systematic review and meta-analysisYuancai Chen0Huikai Qin1Yayun Wu2Huiyan Xu3Jianying Huang4Junqiang Li5Longxian Zhang6https://orcid.org/0000-0001-9310-1975College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, P. R. ChinaCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, P. R. ChinaCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, P. R. ChinaCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, P. R. ChinaCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, P. R. ChinaCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, P. R. ChinaCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, P. R. ChinaCryptosporidium spp. are significant opportunistic pathogens causing diarrhoea in humans and animals. Pigs are one of the most important potential hosts for Cryptosporidium. We evaluated the prevalence of Cryptosporidium in pigs globally using published information and a random-effects model. In total, 131 datasets from 36 countries were included in the final quantitative analysis. The global prevalence of Cryptosporidium in pigs was 16.3% (8560/64 809; 95% confidence interval [CI] 15.0–17.6%). The highest prevalence of Cryptosporidium in pigs was 40.8% (478/1271) in Africa. Post-weaned pigs had a significantly higher prevalence (25.8%; 2739/11 824) than pre-weaned, fattening and adult pigs. The prevalence of Cryptosporidium was higher in pigs with no diarrhoea (12.2%; 371/3501) than in pigs that had diarrhoea (8.0%; 348/4874). Seven Cryptosporidium species (Cryptosporidium scrofarum, Cryptosporidium suis, Cryptosporidium parvum, Cryptosporidium muris, Cryptosporidium tyzzeri, Cryptosporidium andersoni and Cryptosporidium struthioni) were detected in pigs globally. The proportion of C. scrofarum was 34.3% (1491/4351); the proportion of C. suis was 31.8% (1385/4351) and the proportion of C. parvum was 2.3% (98/4351). The influence of different geographic factors (latitude, longitude, mean yearly temperature, mean yearly relative humidity and mean yearly precipitation) on the infection rate of Cryptosporidium in pigs was also analysed. The results indicate that C. suis is the dominant species in pre-weaned pigs, while C. scrofarum is the dominant species in fattening and adult pigs. The findings highlight the role of pigs as possible potential hosts of zoonotic cryptosporidiosis and the need for additional studies on the prevalence, transmission and control of Cryptosporidium in pigs.https://www.cambridge.org/core/product/identifier/S0031182023000276/type/journal_articleCryptosporidiummeta-analysispigprevalence |
| spellingShingle | Yuancai Chen Huikai Qin Yayun Wu Huiyan Xu Jianying Huang Junqiang Li Longxian Zhang Global prevalence of Cryptosporidium spp. in pigs: a systematic review and meta-analysis Parasitology Cryptosporidium meta-analysis pig prevalence |
| title | Global prevalence of Cryptosporidium spp. in pigs: a systematic review and meta-analysis |
| title_full | Global prevalence of Cryptosporidium spp. in pigs: a systematic review and meta-analysis |
| title_fullStr | Global prevalence of Cryptosporidium spp. in pigs: a systematic review and meta-analysis |
| title_full_unstemmed | Global prevalence of Cryptosporidium spp. in pigs: a systematic review and meta-analysis |
| title_short | Global prevalence of Cryptosporidium spp. in pigs: a systematic review and meta-analysis |
| title_sort | global prevalence of cryptosporidium spp in pigs a systematic review and meta analysis |
| topic | Cryptosporidium meta-analysis pig prevalence |
| url | https://www.cambridge.org/core/product/identifier/S0031182023000276/type/journal_article |
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