Successful antibiotic stewardship in hospitalised children in a developing nation
Objectives: Increasing antimicrobial resistance has become a looming threat to paediatric health and, therefore, health facilities are obliged to practice antimicrobial stewardship. This study was undertaken to review stewardship adherence in the Department of Pediatrics at the Central Hospital, Pre...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-12-01
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| Series: | Journal of Global Antimicrobial Resistance |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213716520302459 |
| _version_ | 1818670988783517696 |
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| author | Fatima Mustafa L.A. Koekemoer Robin J. Green Astrid C. Turner Piet Becker Gertruida van Biljon |
| author_facet | Fatima Mustafa L.A. Koekemoer Robin J. Green Astrid C. Turner Piet Becker Gertruida van Biljon |
| author_sort | Fatima Mustafa |
| collection | DOAJ |
| description | Objectives: Increasing antimicrobial resistance has become a looming threat to paediatric health and, therefore, health facilities are obliged to practice antimicrobial stewardship. This study was undertaken to review stewardship adherence in the Department of Pediatrics at the Central Hospital, Pretoria, South Africa. Methods: Antibiotic prescriptions of children admitted to hospital were reviewed for consistency with the national essential medicines list from January 2017 to January 2019. Medical records of children were reviewed to obtain the primary diagnosis, requested laboratory investigations and antibiotic prescription practices. The management was adjudicated as consistent with policy by a score system. Results: This study reveals that management was in agreement with standard guidelines in 69.3% of cases, with a range of 33–77%. From the start of the study in January 2017 to the final date in January 2019 there was a significant increase in the number of patients with respiratory tract infections who were treated correctly, increasing from 41% to 73% at study end. Conclusions: This study is the first to report the success of antibiotic stewardship in children admitted to a tertiary hospital in South Africa. However, it is critical that antibiotic stewardship be continued and antibiotic prescriptions be aligned with guidelines. |
| first_indexed | 2024-12-17T07:16:51Z |
| format | Article |
| id | doaj.art-06958f8b04f849afb5e59ee9fc0cc62e |
| institution | Directory Open Access Journal |
| issn | 2213-7165 |
| language | English |
| last_indexed | 2024-12-17T07:16:51Z |
| publishDate | 2020-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Global Antimicrobial Resistance |
| spelling | doaj.art-06958f8b04f849afb5e59ee9fc0cc62e2022-12-21T21:58:52ZengElsevierJournal of Global Antimicrobial Resistance2213-71652020-12-0123217220Successful antibiotic stewardship in hospitalised children in a developing nationFatima Mustafa0L.A. Koekemoer1Robin J. Green2Astrid C. Turner3Piet Becker4Gertruida van Biljon5Department of Paediaitrics and Child Health, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South Africa; Corresponding author at: Department of Paediatrics and Child Health, University of Pretoria, Steve Biko Hospital, Steve Biko Street, Pretoria, 0001, South Africa.Department of Paediaitrics and Child Health, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South AfricaDepartment of Paediaitrics and Child Health, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South AfricaSchool of Health Systems and Public Health, University of Pretoria, Pretoria, South AfricaDeans Office, Faculty of Health Sciences, University of Pretoria, Pretoria, South AfricaDepartment of Paediaitrics and Child Health, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South AfricaObjectives: Increasing antimicrobial resistance has become a looming threat to paediatric health and, therefore, health facilities are obliged to practice antimicrobial stewardship. This study was undertaken to review stewardship adherence in the Department of Pediatrics at the Central Hospital, Pretoria, South Africa. Methods: Antibiotic prescriptions of children admitted to hospital were reviewed for consistency with the national essential medicines list from January 2017 to January 2019. Medical records of children were reviewed to obtain the primary diagnosis, requested laboratory investigations and antibiotic prescription practices. The management was adjudicated as consistent with policy by a score system. Results: This study reveals that management was in agreement with standard guidelines in 69.3% of cases, with a range of 33–77%. From the start of the study in January 2017 to the final date in January 2019 there was a significant increase in the number of patients with respiratory tract infections who were treated correctly, increasing from 41% to 73% at study end. Conclusions: This study is the first to report the success of antibiotic stewardship in children admitted to a tertiary hospital in South Africa. However, it is critical that antibiotic stewardship be continued and antibiotic prescriptions be aligned with guidelines.http://www.sciencedirect.com/science/article/pii/S2213716520302459Antimicrobial stewardshipAcademic hospitalChildren |
| spellingShingle | Fatima Mustafa L.A. Koekemoer Robin J. Green Astrid C. Turner Piet Becker Gertruida van Biljon Successful antibiotic stewardship in hospitalised children in a developing nation Journal of Global Antimicrobial Resistance Antimicrobial stewardship Academic hospital Children |
| title | Successful antibiotic stewardship in hospitalised children in a developing nation |
| title_full | Successful antibiotic stewardship in hospitalised children in a developing nation |
| title_fullStr | Successful antibiotic stewardship in hospitalised children in a developing nation |
| title_full_unstemmed | Successful antibiotic stewardship in hospitalised children in a developing nation |
| title_short | Successful antibiotic stewardship in hospitalised children in a developing nation |
| title_sort | successful antibiotic stewardship in hospitalised children in a developing nation |
| topic | Antimicrobial stewardship Academic hospital Children |
| url | http://www.sciencedirect.com/science/article/pii/S2213716520302459 |
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