DMRT1 is a testis-determining gene in rabbits and is also essential for female fertility

DMRT1 is a testis-determining gene in rabbits and is also essential for female fertility

DMRT1 is the testis-determining factor in several species of vertebrates, but its involvement in mammalian testes differentiation, where SRY is the testis-determining gene, remains ambiguous. So far, DMRT1 loss-of-function has been described in two mammalian species and induces different phenotypes:...

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Bibliographic Details
Main Authors: Emilie Dujardin, Marjolaine André, Aurélie Dewaele, Béatrice Mandon-Pépin, Francis Poulat, Anne Frambourg, Dominique Thépot, Luc Jouneau, Geneviève Jolivet, Eric Pailhoux, Maëlle Pannetier
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-10-01
Series:eLife
Subjects:
rabbit
sex determination
fertility
gonads
Online Access:https://elifesciences.org/articles/89284

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