Circular RNAs: Biogenesis, Function and Role in Human Diseases

Circular RNAs: Biogenesis, Function and Role in Human Diseases

Circular RNAs (circRNAs) are currently classed as non-coding RNA (ncRNA) that, unlike linear RNAs, form covalently closed continuous loops and act as gene regulators in mammals. They were originally thought to represent errors in splicing and considered to be of low abundance, however, there is now...

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Bibliographic Details
Main Authors: John Greene, Anne-Marie Baird, Lauren Brady, Marvin Lim, Steven G. Gray, Raymond McDermott, Stephen P. Finn
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
circRNAs
non-coding RNA
miRNA
diseases
cancer
Online Access:http://journal.frontiersin.org/article/10.3389/fmolb.2017.00038/full

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