Hi-C analysis of genomic contacts revealed karyotype abnormalities in chicken HD3 cell line

Hi-C analysis of genomic contacts revealed karyotype abnormalities in chicken HD3 cell line

Abstract Background Karyotype abnormalities are frequent in immortalized continuous cell lines either transformed or derived from primary tumors. Chromosomal rearrangements can cause dramatic changes in gene expression and affect cellular phenotype and behavior during in vitro culture. Structural va...

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Bibliographic Details
Main Authors: A. Maslova, V. Plotnikov, M. Nuriddinov, M. Gridina, V. Fishman, A. Krasikova
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Genomics
Subjects:
HD3
A/B compartments
Avian karyotype
Chicken cells
Chromosome rearrangement
Chromosome translocation
Online Access:https://doi.org/10.1186/s12864-023-09158-y

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