Low prevalence of human enteropathogenic Yersinia spp. in brown rats (Rattus norvegicus) in Flanders.
Brown rats (Rattus norvegicus) have been identified as potential carriers of Yersinia enterocolitica and Y. pseudotuberculosis, the etiological agents of yersiniosis, the third most reported bacterial zoonosis in Europe. Enteropathogenic Yersinia spp. are most often isolated from rats during yersini...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5389835?pdf=render |
| _version_ | 1818940816867983360 |
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| author | Lieze Oscar Rouffaer Kristof Baert Anne-Marie Van den Abeele Ivo Cox Gerty Vanantwerpen Lieven De Zutter Diederik Strubbe Katleen Vranckx Luc Lens Freddy Haesebrouck Michel Delmée Frank Pasmans An Martel |
| author_facet | Lieze Oscar Rouffaer Kristof Baert Anne-Marie Van den Abeele Ivo Cox Gerty Vanantwerpen Lieven De Zutter Diederik Strubbe Katleen Vranckx Luc Lens Freddy Haesebrouck Michel Delmée Frank Pasmans An Martel |
| author_sort | Lieze Oscar Rouffaer |
| collection | DOAJ |
| description | Brown rats (Rattus norvegicus) have been identified as potential carriers of Yersinia enterocolitica and Y. pseudotuberculosis, the etiological agents of yersiniosis, the third most reported bacterial zoonosis in Europe. Enteropathogenic Yersinia spp. are most often isolated from rats during yersiniosis cases in animals and humans, and from rats inhabiting farms and slaughterhouses. Information is however lacking regarding the extent to which rats act as carriers of these Yersinia spp.. In 2013, 1088 brown rats across Flanders, Belgium, were tested for the presence of Yersinia species by isolation method. Identification was performed using MALDI-TOF MS, PCR on chromosomal- and plasmid-borne virulence genes, biotyping and serotyping. Yersinia spp. were isolated from 38.4% of the rats. Of these, 53.4% were designated Y. enterocolitica, 0.7% Y. pseudotuberculosis and 49.0% other Yersinia species. Two Y. enterocolitica possessing the virF-, ail- and ystA-gene were isolated. Additionally, the ystB-gene was identified in 94.1% of the other Y. enterocolitica isolates, suggestive for biotype 1A. Three of these latter isolates simultaneously possessed the ail-virulence gene. Significantly more Y. enterocolitica were isolated during winter and spring compared to summer. Based on our findings we can conclude that brown rats are frequent carriers for various Yersinia spp., including Y. pseudotuberculosis and (human pathogenic) Y. enterocolitica which are more often isolated during winter and spring. |
| first_indexed | 2024-12-20T06:45:40Z |
| format | Article |
| id | doaj.art-06a679f6dfee4e169c72953ab2df70d5 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T06:45:40Z |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-06a679f6dfee4e169c72953ab2df70d52022-12-21T19:49:42ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01124e017564810.1371/journal.pone.0175648Low prevalence of human enteropathogenic Yersinia spp. in brown rats (Rattus norvegicus) in Flanders.Lieze Oscar RouffaerKristof BaertAnne-Marie Van den AbeeleIvo CoxGerty VanantwerpenLieven De ZutterDiederik StrubbeKatleen VranckxLuc LensFreddy HaesebrouckMichel DelméeFrank PasmansAn MartelBrown rats (Rattus norvegicus) have been identified as potential carriers of Yersinia enterocolitica and Y. pseudotuberculosis, the etiological agents of yersiniosis, the third most reported bacterial zoonosis in Europe. Enteropathogenic Yersinia spp. are most often isolated from rats during yersiniosis cases in animals and humans, and from rats inhabiting farms and slaughterhouses. Information is however lacking regarding the extent to which rats act as carriers of these Yersinia spp.. In 2013, 1088 brown rats across Flanders, Belgium, were tested for the presence of Yersinia species by isolation method. Identification was performed using MALDI-TOF MS, PCR on chromosomal- and plasmid-borne virulence genes, biotyping and serotyping. Yersinia spp. were isolated from 38.4% of the rats. Of these, 53.4% were designated Y. enterocolitica, 0.7% Y. pseudotuberculosis and 49.0% other Yersinia species. Two Y. enterocolitica possessing the virF-, ail- and ystA-gene were isolated. Additionally, the ystB-gene was identified in 94.1% of the other Y. enterocolitica isolates, suggestive for biotype 1A. Three of these latter isolates simultaneously possessed the ail-virulence gene. Significantly more Y. enterocolitica were isolated during winter and spring compared to summer. Based on our findings we can conclude that brown rats are frequent carriers for various Yersinia spp., including Y. pseudotuberculosis and (human pathogenic) Y. enterocolitica which are more often isolated during winter and spring.http://europepmc.org/articles/PMC5389835?pdf=render |
| spellingShingle | Lieze Oscar Rouffaer Kristof Baert Anne-Marie Van den Abeele Ivo Cox Gerty Vanantwerpen Lieven De Zutter Diederik Strubbe Katleen Vranckx Luc Lens Freddy Haesebrouck Michel Delmée Frank Pasmans An Martel Low prevalence of human enteropathogenic Yersinia spp. in brown rats (Rattus norvegicus) in Flanders. PLoS ONE |
| title | Low prevalence of human enteropathogenic Yersinia spp. in brown rats (Rattus norvegicus) in Flanders. |
| title_full | Low prevalence of human enteropathogenic Yersinia spp. in brown rats (Rattus norvegicus) in Flanders. |
| title_fullStr | Low prevalence of human enteropathogenic Yersinia spp. in brown rats (Rattus norvegicus) in Flanders. |
| title_full_unstemmed | Low prevalence of human enteropathogenic Yersinia spp. in brown rats (Rattus norvegicus) in Flanders. |
| title_short | Low prevalence of human enteropathogenic Yersinia spp. in brown rats (Rattus norvegicus) in Flanders. |
| title_sort | low prevalence of human enteropathogenic yersinia spp in brown rats rattus norvegicus in flanders |
| url | http://europepmc.org/articles/PMC5389835?pdf=render |
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