Microwave Assisted Expeditious and Green Cu(II)-Clay Catalyzed Domino One-Pot Three Component Synthesis of 2H-indazoles
A simple and efficient synthesis of 2H-indazoles is achieved from 2-primary amines, bromobenzaldehydes and sodium azide through domino condensation, C–N and N–N bond formations, catalyzed by a heterogeneous Cu(II)-Clay catalyst. The recyclable heterogeneous Cu(II)-Clay catalyst exhibited a remarkabl...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Masyarakat Katalis Indonesia - Indonesian Catalyst Society (MKICS)
2018-04-01
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| Series: | Bulletin of Chemical Reaction Engineering & Catalysis |
| Subjects: | |
| Online Access: | https://journal.bcrec.id/index.php/bcrec/article/view/963 |
| _version_ | 1797677794459648000 |
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| author | Bashir Ahmad Dar Syed Wasim Safvi Masood Ahmad Rizvi |
| author_facet | Bashir Ahmad Dar Syed Wasim Safvi Masood Ahmad Rizvi |
| author_sort | Bashir Ahmad Dar |
| collection | DOAJ |
| description | A simple and efficient synthesis of 2H-indazoles is achieved from 2-primary amines, bromobenzaldehydes and sodium azide through domino condensation, C–N and N–N bond formations, catalyzed by a heterogeneous Cu(II)-Clay catalyst. The recyclable heterogeneous Cu(II)-Clay catalyst exhibited a remarkable activity for the title reaction without any additives. An assortment of structurally diverse 2H-indazoles were prepared in good to excellent yields from easily available starting materials by using this protocol. The Cu(II)-Clay catalyst was characterized by using X-Ray Diffraction (XRD), Scanning Electron Microscopy (SEM), and Brunauer-Emmett-Teller (BET) techniques. |
| first_indexed | 2024-03-11T22:50:20Z |
| format | Article |
| id | doaj.art-06a69d05b0e3413b86584b469e108f60 |
| institution | Directory Open Access Journal |
| issn | 1978-2993 |
| language | English |
| last_indexed | 2024-03-11T22:50:20Z |
| publishDate | 2018-04-01 |
| publisher | Masyarakat Katalis Indonesia - Indonesian Catalyst Society (MKICS) |
| record_format | Article |
| series | Bulletin of Chemical Reaction Engineering & Catalysis |
| spelling | doaj.art-06a69d05b0e3413b86584b469e108f602023-09-22T03:45:14ZengMasyarakat Katalis Indonesia - Indonesian Catalyst Society (MKICS)Bulletin of Chemical Reaction Engineering & Catalysis1978-29932018-04-01131828810.9767/bcrec.13.1.963.82-88900Microwave Assisted Expeditious and Green Cu(II)-Clay Catalyzed Domino One-Pot Three Component Synthesis of 2H-indazolesBashir Ahmad Dar0Syed Wasim Safvi1Masood Ahmad Rizvi2Department of Chemistry, Govt., Degree College Boys, Sopore Jammu & Kashmir, 193201, IndiaDepartment of Chemistry, University of Kashmir, Hazratbal, Srinagar, J&K, IndiaDepartment of Chemistry, University of Kashmir, Hazratbal, Srinagar, J&K, IndiaA simple and efficient synthesis of 2H-indazoles is achieved from 2-primary amines, bromobenzaldehydes and sodium azide through domino condensation, C–N and N–N bond formations, catalyzed by a heterogeneous Cu(II)-Clay catalyst. The recyclable heterogeneous Cu(II)-Clay catalyst exhibited a remarkable activity for the title reaction without any additives. An assortment of structurally diverse 2H-indazoles were prepared in good to excellent yields from easily available starting materials by using this protocol. The Cu(II)-Clay catalyst was characterized by using X-Ray Diffraction (XRD), Scanning Electron Microscopy (SEM), and Brunauer-Emmett-Teller (BET) techniques.https://journal.bcrec.id/index.php/bcrec/article/view/9632h-indazolescopper catalystmulticomponent reactiongreen synthesisneat protocol |
| spellingShingle | Bashir Ahmad Dar Syed Wasim Safvi Masood Ahmad Rizvi Microwave Assisted Expeditious and Green Cu(II)-Clay Catalyzed Domino One-Pot Three Component Synthesis of 2H-indazoles Bulletin of Chemical Reaction Engineering & Catalysis 2h-indazoles copper catalyst multicomponent reaction green synthesis neat protocol |
| title | Microwave Assisted Expeditious and Green Cu(II)-Clay Catalyzed Domino One-Pot Three Component Synthesis of 2H-indazoles |
| title_full | Microwave Assisted Expeditious and Green Cu(II)-Clay Catalyzed Domino One-Pot Three Component Synthesis of 2H-indazoles |
| title_fullStr | Microwave Assisted Expeditious and Green Cu(II)-Clay Catalyzed Domino One-Pot Three Component Synthesis of 2H-indazoles |
| title_full_unstemmed | Microwave Assisted Expeditious and Green Cu(II)-Clay Catalyzed Domino One-Pot Three Component Synthesis of 2H-indazoles |
| title_short | Microwave Assisted Expeditious and Green Cu(II)-Clay Catalyzed Domino One-Pot Three Component Synthesis of 2H-indazoles |
| title_sort | microwave assisted expeditious and green cu ii clay catalyzed domino one pot three component synthesis of 2h indazoles |
| topic | 2h-indazoles copper catalyst multicomponent reaction green synthesis neat protocol |
| url | https://journal.bcrec.id/index.php/bcrec/article/view/963 |
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