Cholesterol Regulates Syntaxin 6 Trafficking at trans-Golgi Network Endosomal Boundaries

Cholesterol Regulates Syntaxin 6 Trafficking at trans-Golgi Network Endosomal Boundaries

Inhibition of cholesterol export from late endosomes causes cellular cholesterol imbalance, including cholesterol depletion in the trans-Golgi network (TGN). Here, using Chinese hamster ovary (CHO) Niemann-Pick type C1 (NPC1) mutant cell lines and human NPC1 mutant fibroblasts, we show that altered...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Meritxell Reverter, Carles Rentero, Ana Garcia-Melero, Monira Hoque, Sandra Vilà de Muga, Anna Álvarez-Guaita, James R.W. Conway, Peta Wood, Rose Cairns, Lilia Lykopoulou, Daniel Grinberg, Lluïsa Vilageliu, Marta Bosch, Joerg Heeren, Juan Blasi, Paul Timpson, Albert Pol, Francesc Tebar, Rachael Z. Murray, Thomas Grewal, Carlos Enrich
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Elsevier 2014-05-01
Sarja:Cell Reports
Linkit:http://www.sciencedirect.com/science/article/pii/S221112471400240X

Internet

http://www.sciencedirect.com/science/article/pii/S221112471400240X

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