Anogenital herpesvirus infection: focus on HIV-positive patients
The annual growth in the number of people living with HIV infection inevitably leads to an increase in the number of cases of any type of comorbidity. The article analyzes modern epidemiological, clinical, therapeutic aspects of anogenital herpes simplex virus infection (AHVI) in HIV-positive patien...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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State Scientific Center of Dermatovenereology and Cosmetology
2023-10-01
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| Series: | Vestnik Dermatologii i Venerologii |
| Subjects: | |
| Online Access: | https://vestnikdv.ru/jour/article/viewFile/7753/pdf_2 |
| _version_ | 1827768298552426496 |
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| author | Sergey V. Prozherin Anzhelika S. Podymova |
| author_facet | Sergey V. Prozherin Anzhelika S. Podymova |
| author_sort | Sergey V. Prozherin |
| collection | DOAJ |
| description | The annual growth in the number of people living with HIV infection inevitably leads to an increase in the number of cases of any type of comorbidity. The article analyzes modern epidemiological, clinical, therapeutic aspects of anogenital herpes simplex virus infection (AHVI) in HIV-positive patients. Human immunodeficiency virus (HIV) and herpes simplex virus 2 (HSV-2) combine epidemiological and biological synergy. Concomitant anogenital herpes increases the risk of HIV infection by 2.74.7 times, and also contributes to its transmission through unprotected sexual intercourse. In HIV-infected patients with AHVI, the genital excretion of HSV-2 is increased. Among HIV-positive individuals, the seroprevalence of HSV-2 exceeds the population figures by 1.93.8 times. The incidence of AHVI in a cohort of Russians with a positive HIV status is 57.8 times higher than in the general population. The review demonstrates that both infections can have a negative mutual influence on the clinical course of each other. Particular emphasis is placed on the timely diagnosis of cases of coinfection. Based on the current regulatory documents, the authors developed and presented an algorithm for testing for HIV in patients with a newly diagnosed anogenital herpes. |
| first_indexed | 2024-03-11T12:10:21Z |
| format | Article |
| id | doaj.art-06a9c4e878ce4decba79c4a491f17148 |
| institution | Directory Open Access Journal |
| issn | 0042-4609 2313-6294 |
| language | English |
| last_indexed | 2024-03-11T12:10:21Z |
| publishDate | 2023-10-01 |
| publisher | State Scientific Center of Dermatovenereology and Cosmetology |
| record_format | Article |
| series | Vestnik Dermatologii i Venerologii |
| spelling | doaj.art-06a9c4e878ce4decba79c4a491f171482023-11-07T14:10:01ZengState Scientific Center of Dermatovenereology and CosmetologyVestnik Dermatologii i Venerologii0042-46092313-62942023-10-01994849510.25208/vdv77531236Anogenital herpesvirus infection: focus on HIV-positive patientsSergey V. Prozherin0https://orcid.org/0000-0001-9956-4700Anzhelika S. Podymova1https://orcid.org/0000-0001-7345-0801Sverdlovsk Regional Center for Prevention and Control of AIDSSverdlovsk Regional Center for Prevention and Control of AIDSThe annual growth in the number of people living with HIV infection inevitably leads to an increase in the number of cases of any type of comorbidity. The article analyzes modern epidemiological, clinical, therapeutic aspects of anogenital herpes simplex virus infection (AHVI) in HIV-positive patients. Human immunodeficiency virus (HIV) and herpes simplex virus 2 (HSV-2) combine epidemiological and biological synergy. Concomitant anogenital herpes increases the risk of HIV infection by 2.74.7 times, and also contributes to its transmission through unprotected sexual intercourse. In HIV-infected patients with AHVI, the genital excretion of HSV-2 is increased. Among HIV-positive individuals, the seroprevalence of HSV-2 exceeds the population figures by 1.93.8 times. The incidence of AHVI in a cohort of Russians with a positive HIV status is 57.8 times higher than in the general population. The review demonstrates that both infections can have a negative mutual influence on the clinical course of each other. Particular emphasis is placed on the timely diagnosis of cases of coinfection. Based on the current regulatory documents, the authors developed and presented an algorithm for testing for HIV in patients with a newly diagnosed anogenital herpes.https://vestnikdv.ru/jour/article/viewFile/7753/pdf_2genital herpeshiv infectionherpes simplex virus type 2hsv-2 |
| spellingShingle | Sergey V. Prozherin Anzhelika S. Podymova Anogenital herpesvirus infection: focus on HIV-positive patients Vestnik Dermatologii i Venerologii genital herpes hiv infection herpes simplex virus type 2 hsv-2 |
| title | Anogenital herpesvirus infection: focus on HIV-positive patients |
| title_full | Anogenital herpesvirus infection: focus on HIV-positive patients |
| title_fullStr | Anogenital herpesvirus infection: focus on HIV-positive patients |
| title_full_unstemmed | Anogenital herpesvirus infection: focus on HIV-positive patients |
| title_short | Anogenital herpesvirus infection: focus on HIV-positive patients |
| title_sort | anogenital herpesvirus infection focus on hiv positive patients |
| topic | genital herpes hiv infection herpes simplex virus type 2 hsv-2 |
| url | https://vestnikdv.ru/jour/article/viewFile/7753/pdf_2 |
| work_keys_str_mv | AT sergeyvprozherin anogenitalherpesvirusinfectionfocusonhivpositivepatients AT anzhelikaspodymova anogenitalherpesvirusinfectionfocusonhivpositivepatients |