Inactivation of p15INK4b in chronic arsenic poisoning cases

Inactivation of p15INK4b in chronic arsenic poisoning cases

Arsenic exposure from burning high arsenic-containing coal has been associated with human skin lesion and cancer. However, the mechanisms of arsenic-related carcinogenesis are not fully understood. Inactivation of critical tumor suppression genes by epigenetic regulation or genetic modification migh...

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Bibliographic Details
Main Authors:	Aihua Zhang, Chen Gao, Xue Han, Lifang Wang, Chun Yu, Xiaowen Zeng, Liping Chen, Daochuan Li, Wen Chen
Format:	Article
Language:	English
Published:	Elsevier 2014-01-01
Series:	Toxicology Reports
Subjects:	Arsenic Domestic coal use Skin lesions p15INK4b DNA methylation Homozygous deletion
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214750014000705

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