Expert consensus on fertility preservation in hematopoietic stem cell transplantation in girls in China

Aims: Preconditioning before hematopoietic stem cell transplantation (HSCT) seriously damages the ovarian function and causes female infertility. This consensus focuses on the fertility preservation(FP) for girls needing HSCT, aim to make doctors in different disciplines aware of the importance, nec...

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主要作者: X. Ruan
格式: 文件
语言:English
出版: Taylor & Francis Group 2023-12-01
丛编:Gynecological Endocrinology
主题:
在线阅读:https://www.tandfonline.com/doi/10.1080/09513590.2022.2146671
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author X. Ruan
author_facet X. Ruan
author_sort X. Ruan
collection DOAJ
description Aims: Preconditioning before hematopoietic stem cell transplantation (HSCT) seriously damages the ovarian function and causes female infertility. This consensus focuses on the fertility preservation(FP) for girls needing HSCT, aim to make doctors in different disciplines aware of the importance, necessity and technique of ovarian protection.Materials and methods: Summarizing relevant literature and organizing multidisciplinary experts, including obstetrics and gynecology, reproductive medicine, oncology, pediatrics and hematology for full discussion.Results: Individuals exposed to HSCT in childhood are at higher risk of loss of fertility. Considering the high risk of premature ovarian insufficiency (POI) after conditioning and negative impact of POI on fertility, physical and mental health, it is absolutely necessary to protect fertility before HSCT conditioning. Ovarian tissue cryopreservation is the main fertility preservation option for these population.Conclusions: Fertility preservation before HSCT conditioning is crucial. Ovarian tissue cryopreservation is often the only option for these population.
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spelling doaj.art-06b3aa3b51dd4f5f8dfa4b8bf3f4e5c52024-08-07T16:02:52ZengTaylor & Francis GroupGynecological Endocrinology0951-35901473-07662023-12-0139110.1080/09513590.2022.2146671Expert consensus on fertility preservation in hematopoietic stem cell transplantation in girls in ChinaX. Ruan0Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University. Beijing Maternal and Child Health Care Hospital, Beijing, ChinaAims: Preconditioning before hematopoietic stem cell transplantation (HSCT) seriously damages the ovarian function and causes female infertility. This consensus focuses on the fertility preservation(FP) for girls needing HSCT, aim to make doctors in different disciplines aware of the importance, necessity and technique of ovarian protection.Materials and methods: Summarizing relevant literature and organizing multidisciplinary experts, including obstetrics and gynecology, reproductive medicine, oncology, pediatrics and hematology for full discussion.Results: Individuals exposed to HSCT in childhood are at higher risk of loss of fertility. Considering the high risk of premature ovarian insufficiency (POI) after conditioning and negative impact of POI on fertility, physical and mental health, it is absolutely necessary to protect fertility before HSCT conditioning. Ovarian tissue cryopreservation is the main fertility preservation option for these population.Conclusions: Fertility preservation before HSCT conditioning is crucial. Ovarian tissue cryopreservation is often the only option for these population.https://www.tandfonline.com/doi/10.1080/09513590.2022.2146671Hematopoietic stem cell transplantationfertility preservationovarian tissue cryopreservationexpert consensusovaryinfertility
spellingShingle X. Ruan
Expert consensus on fertility preservation in hematopoietic stem cell transplantation in girls in China
Gynecological Endocrinology
Hematopoietic stem cell transplantation
fertility preservation
ovarian tissue cryopreservation
expert consensus
ovary
infertility
title Expert consensus on fertility preservation in hematopoietic stem cell transplantation in girls in China
title_full Expert consensus on fertility preservation in hematopoietic stem cell transplantation in girls in China
title_fullStr Expert consensus on fertility preservation in hematopoietic stem cell transplantation in girls in China
title_full_unstemmed Expert consensus on fertility preservation in hematopoietic stem cell transplantation in girls in China
title_short Expert consensus on fertility preservation in hematopoietic stem cell transplantation in girls in China
title_sort expert consensus on fertility preservation in hematopoietic stem cell transplantation in girls in china
topic Hematopoietic stem cell transplantation
fertility preservation
ovarian tissue cryopreservation
expert consensus
ovary
infertility
url https://www.tandfonline.com/doi/10.1080/09513590.2022.2146671
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