Which treatment strategy is preferred in the octogenarians with acute coronary syndrome?

Objective: To compare the efficacy of invasive and conservative strategy in the management of octogenarians with acute coronary syndrome. Methods: The retrospective study was conducted after approval from the ethics review committee of University of Health Sciences, Derince Training and Research...

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Main Authors: Gulay Aydin, Ebru Golcuk, Gulistan Bahat
Format: Article
Language:English
Published: Pakistan Medical Association 2023-08-01
Series:Journal of the Pakistan Medical Association
Subjects:
Online Access:https://ojs.jpma.org.pk/index.php/public_html/article/view/6972
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author Gulay Aydin
Ebru Golcuk
Gulistan Bahat
author_facet Gulay Aydin
Ebru Golcuk
Gulistan Bahat
author_sort Gulay Aydin
collection DOAJ
description Objective: To compare the efficacy of invasive and conservative strategy in the management of octogenarians with acute coronary syndrome. Methods: The retrospective study was conducted after approval from the ethics review committee of University of Health Sciences, Derince Training and Research Hospital, Turkey and comprised data from April 2020 to April 2021 related to octogenarian patients of either gender admitted to University of Health Sciences, Darica Farabi Training and Research Hospital, Turkey with acute coronary syndrome diagnosis. The data was divided into invasive group A and conservative group B. Data was analysed using SPSS 25. Results: Of the 168 patients with median age 84(interquartile range: 81-86 years), there were 25(14.9%) in group A; 14(56%) males and 11(44%) females. There were 143(85.1%) patients in group B; 70(49%) males and 73(51%) females. Overall mortality was 111(66.1%); 11(44%) in group A, and 100(69.9%) in group B (p=0.012). Elevated alanine aminotransferase and invasive strategy were independent factors associated with mortality (p<0.05). Conclusion: The invasive strategy in the management of octogenarian patients presenting with acute coronary syndrome was found to be more efficient compared to the conservative strategy. Key Words: Octogenarians, Acute coronary syndrome, Mortality.
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spelling doaj.art-06b3dd57115c450a9e98616f49b743552023-08-20T04:48:00ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822023-08-0173910.47391/JPMA.6972Which treatment strategy is preferred in the octogenarians with acute coronary syndrome?Gulay Aydin0Ebru Golcuk1Gulistan Bahat2Department of Cardiology, University of Health Sciences, Darica Farabi Training and Research Hospital, TurkeyDepartment of Cardiology, University of Health Sciences, Darica Farabi Training and Research Hospital, TurkeyDepartment of Internal Medicine, Istanbul University, Istanbul Medical School, Istanbul, Turkey Objective: To compare the efficacy of invasive and conservative strategy in the management of octogenarians with acute coronary syndrome. Methods: The retrospective study was conducted after approval from the ethics review committee of University of Health Sciences, Derince Training and Research Hospital, Turkey and comprised data from April 2020 to April 2021 related to octogenarian patients of either gender admitted to University of Health Sciences, Darica Farabi Training and Research Hospital, Turkey with acute coronary syndrome diagnosis. The data was divided into invasive group A and conservative group B. Data was analysed using SPSS 25. Results: Of the 168 patients with median age 84(interquartile range: 81-86 years), there were 25(14.9%) in group A; 14(56%) males and 11(44%) females. There were 143(85.1%) patients in group B; 70(49%) males and 73(51%) females. Overall mortality was 111(66.1%); 11(44%) in group A, and 100(69.9%) in group B (p=0.012). Elevated alanine aminotransferase and invasive strategy were independent factors associated with mortality (p<0.05). Conclusion: The invasive strategy in the management of octogenarian patients presenting with acute coronary syndrome was found to be more efficient compared to the conservative strategy. Key Words: Octogenarians, Acute coronary syndrome, Mortality. https://ojs.jpma.org.pk/index.php/public_html/article/view/6972OctogenariansAcute coronary syndromeMortality
spellingShingle Gulay Aydin
Ebru Golcuk
Gulistan Bahat
Which treatment strategy is preferred in the octogenarians with acute coronary syndrome?
Journal of the Pakistan Medical Association
Octogenarians
Acute coronary syndrome
Mortality
title Which treatment strategy is preferred in the octogenarians with acute coronary syndrome?
title_full Which treatment strategy is preferred in the octogenarians with acute coronary syndrome?
title_fullStr Which treatment strategy is preferred in the octogenarians with acute coronary syndrome?
title_full_unstemmed Which treatment strategy is preferred in the octogenarians with acute coronary syndrome?
title_short Which treatment strategy is preferred in the octogenarians with acute coronary syndrome?
title_sort which treatment strategy is preferred in the octogenarians with acute coronary syndrome
topic Octogenarians
Acute coronary syndrome
Mortality
url https://ojs.jpma.org.pk/index.php/public_html/article/view/6972
work_keys_str_mv AT gulayaydin whichtreatmentstrategyispreferredintheoctogenarianswithacutecoronarysyndrome
AT ebrugolcuk whichtreatmentstrategyispreferredintheoctogenarianswithacutecoronarysyndrome
AT gulistanbahat whichtreatmentstrategyispreferredintheoctogenarianswithacutecoronarysyndrome