Updates on conventional therapies for inflammatory bowel diseases: 5-aminosalicylates, corticosteroids, immunomodulators, and anti-TNF-α

The incidence and prevalence of inflammatory bowel diseases (IBDs) are rapidly increasing worldwide. IBDs are considered an emerging problem not only in Western countries but also in developing counties. The relapses and complications of active IBD mandate various medications. Nevertheless, hospital...

Full description

Bibliographic Details
Main Authors: Jihye Park, Jae Hee Cheon
Format: Article
Language:English
Published: The Korean Association of Internal Medicine 2022-09-01
Series:The Korean Journal of Internal Medicine
Subjects:
Online Access:http://kjim.org/upload/pdf/kjim-2022-132.pdf
_version_ 1828112450544730112
author Jihye Park
Jae Hee Cheon
author_facet Jihye Park
Jae Hee Cheon
author_sort Jihye Park
collection DOAJ
description The incidence and prevalence of inflammatory bowel diseases (IBDs) are rapidly increasing worldwide. IBDs are considered an emerging problem not only in Western countries but also in developing counties. The relapses and complications of active IBD mandate various medications. Nevertheless, hospitalization, emergency room visits, or surgery may be required, resulting in a socioeconomic burden. Great advances have been made in the development of new therapeutic options for IBD to achieve induction and maintenance remission. Nevertheless, conventional therapy is still the mainstay in the treatment of IBD. This review article provides an update on recent advances in conventional therapies, including 5-aminosalicylates, corticosteroids, immunomodulators, and anti-tumor necrosis factor-α agents to treat IBD.
first_indexed 2024-04-11T11:49:25Z
format Article
id doaj.art-06b90a1663b34e9dbb03961ed495223a
institution Directory Open Access Journal
issn 1226-3303
2005-6648
language English
last_indexed 2024-04-11T11:49:25Z
publishDate 2022-09-01
publisher The Korean Association of Internal Medicine
record_format Article
series The Korean Journal of Internal Medicine
spelling doaj.art-06b90a1663b34e9dbb03961ed495223a2022-12-22T04:25:25ZengThe Korean Association of Internal MedicineThe Korean Journal of Internal Medicine1226-33032005-66482022-09-0137589590510.3904/kjim.2022.132170711Updates on conventional therapies for inflammatory bowel diseases: 5-aminosalicylates, corticosteroids, immunomodulators, and anti-TNF-αJihye Park0Jae Hee Cheon1 Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea Department of Internal Medicine, Yonsei University College of Medicine, Seoul, KoreaThe incidence and prevalence of inflammatory bowel diseases (IBDs) are rapidly increasing worldwide. IBDs are considered an emerging problem not only in Western countries but also in developing counties. The relapses and complications of active IBD mandate various medications. Nevertheless, hospitalization, emergency room visits, or surgery may be required, resulting in a socioeconomic burden. Great advances have been made in the development of new therapeutic options for IBD to achieve induction and maintenance remission. Nevertheless, conventional therapy is still the mainstay in the treatment of IBD. This review article provides an update on recent advances in conventional therapies, including 5-aminosalicylates, corticosteroids, immunomodulators, and anti-tumor necrosis factor-α agents to treat IBD.http://kjim.org/upload/pdf/kjim-2022-132.pdfinflammatory bowel diseasesmesalamineadrenal cortex hormonesimmunologic factorsanti-tnf agents
spellingShingle Jihye Park
Jae Hee Cheon
Updates on conventional therapies for inflammatory bowel diseases: 5-aminosalicylates, corticosteroids, immunomodulators, and anti-TNF-α
The Korean Journal of Internal Medicine
inflammatory bowel diseases
mesalamine
adrenal cortex hormones
immunologic factors
anti-tnf agents
title Updates on conventional therapies for inflammatory bowel diseases: 5-aminosalicylates, corticosteroids, immunomodulators, and anti-TNF-α
title_full Updates on conventional therapies for inflammatory bowel diseases: 5-aminosalicylates, corticosteroids, immunomodulators, and anti-TNF-α
title_fullStr Updates on conventional therapies for inflammatory bowel diseases: 5-aminosalicylates, corticosteroids, immunomodulators, and anti-TNF-α
title_full_unstemmed Updates on conventional therapies for inflammatory bowel diseases: 5-aminosalicylates, corticosteroids, immunomodulators, and anti-TNF-α
title_short Updates on conventional therapies for inflammatory bowel diseases: 5-aminosalicylates, corticosteroids, immunomodulators, and anti-TNF-α
title_sort updates on conventional therapies for inflammatory bowel diseases 5 aminosalicylates corticosteroids immunomodulators and anti tnf α
topic inflammatory bowel diseases
mesalamine
adrenal cortex hormones
immunologic factors
anti-tnf agents
url http://kjim.org/upload/pdf/kjim-2022-132.pdf
work_keys_str_mv AT jihyepark updatesonconventionaltherapiesforinflammatoryboweldiseases5aminosalicylatescorticosteroidsimmunomodulatorsandantitnfa
AT jaeheecheon updatesonconventionaltherapiesforinflammatoryboweldiseases5aminosalicylatescorticosteroidsimmunomodulatorsandantitnfa