Association of sex hormones and sex hormone-binding globulin with liver fat in men and women: an observational and Mendelian randomization study

Association of sex hormones and sex hormone-binding globulin with liver fat in men and women: an observational and Mendelian randomization study

BackgroundSex hormones and sex hormone-binding globulin (SHBG) may play a role in fatty liver development. We sought to examine the association of various endogenous sex hormones, including testosterone (T), and SHBG with liver fat using complementary observational and Mendelian randomization (MR) a...

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Bibliographic Details
Main Authors: Xinting Cai, Barbara Thorand, Simon Hohenester, Cornelia Prehn, Alexander Cecil, Jerzy Adamski, Tanja Zeller, Andrea Dennis, Rajarshi Banerjee, Annette Peters, Hanieh Yaghootkar, Jana Nano
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Endocrinology
Subjects:
sex hormones
sex hormone-binding globulin
fatty liver index
liver fat
Mendelian randomization
European cohort
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1223162/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1223162/full

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