In silico comparison of SARS-CoV-2 spike protein-ACE2 binding affinities across species and implications for virus origin

Abstract The devastating impact of the COVID-19 pandemic caused by SARS–coronavirus 2 (SARS-CoV-2) has raised important questions about its origins and the mechanism of its transfer to humans. A further question was whether companion or commercial animals could act as SARS-CoV-2 vectors, with early...

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Bibliographic Details
Main Authors: Sakshi Piplani, Puneet Kumar Singh, David A. Winkler, Nikolai Petrovsky
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92388-5