Dicarbonyl Stress and S-Glutathionylation in Cerebrovascular Diseases: A Focus on Cerebral Cavernous Malformations
Dicarbonyl stress is a dysfunctional state consisting in the abnormal accumulation of reactive α-oxaldehydes leading to increased protein modification. In cells, post-translational changes can also occur through S-glutathionylation, a highly conserved oxidative post-translational modificati...
Main Authors: | Cinzia Antognelli, Andrea Perrelli, Tatiana Armeni, Vincenzo Nicola Talesa, Saverio Francesco Retta |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-02-01
|
Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/9/2/124 |
Similar Items
-
Interplay among Oxidative Stress, Methylglyoxal Pathway and S-Glutathionylation
by: Lidia de Bari, et al.
Published: (2020-12-01) -
Dicarbonyl Stress at the Crossroads of Healthy and Unhealthy Aging
by: Cecilia Nigro, et al.
Published: (2019-07-01) -
Novel dicarbonyl metabolic pathway via mitochondrial ES1 possessing glyoxalase III activity
by: Ginga Ito, et al.
Published: (2023-01-01) -
KRIT1 Loss-Of-Function Associated with Cerebral Cavernous Malformation Disease Leads to Enhanced S-Glutathionylation of Distinct Structural and Regulatory Proteins
by: Laura Cianfruglia, et al.
Published: (2019-01-01) -
Antiglycative Activity and RAGE Expression in Rett Syndrome
by: Valeria Cordone, et al.
Published: (2019-02-01)