R-Modafinil exerts weak effects on spatial memory acquisition and dentate gyrus synaptic plasticity.
Modafinil is a wake promoting drug approved for clinical use and also has cognitive enhancing properties. Its enantiomer R-Modafinil (R-MO) is not well studied in regard to cognitive enhancing properties. Hence we studied its effect in a spatial memory paradigm and its possible effects on dentate gy...
Main Authors: | Bharanidharan Shanmugasundaram, Yogesh D Aher, Jana Aradska, Marija Ilic, Daniel Daba Feyissa, Predrag Kalaba, Nilima Y Aher, Vladimir Dragacevic, Babak Saber Marouf, Thierry Langer, Harald H Sitte, Harald Hoeger, Gert Lubec, Volker Korz |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5482457?pdf=render |
Similar Items
-
Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task
by: Jana Lubec, et al.
Published: (2019-07-01) -
Reduced Levels of the Synaptic Functional Regulator FMRP in Dentate Gyrus of the Aging Sprague-Dawley Rat
by: Roman Smidak, et al.
Published: (2017-11-01) -
Age and cognitive status dependent differences in blood steroid and thyroid hormone concentrations in intact male rats
by: Jovana Maliković, et al.
Published: (2019-06-01) -
Differential effects of wake promoting drug Modafinil in aversive learning paradigms
by: Bharanidharan eShanmugasundaram, et al.
Published: (2015-08-01) -
The effect of modafinil on the rat dopamine transporter and dopamine receptors D1-D3 paralleling cognitive enhancement in the radial arm maze
by: Yasemin eKarabacak, et al.
Published: (2015-08-01)