<i>TERT</i> Promoter Mutations Increase Sense and Antisense Transcription from the <i>TERT</i> Promoter

<i>TERT</i> Promoter Mutations Increase Sense and Antisense Transcription from the <i>TERT</i> Promoter

<b>Background:</b> Chief among mechanisms of telomerase reverse transcriptase (TERT) reactivation is the appearance of mutations in the <i>TERT</i> promoter. The two main <i>TERT</i> promoter mutations are C>T transitions located −146C>T and −124C>T upstr...

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Bibliographic Details
Main Authors: François Hafezi, Lisa Jaxel, Morgane Lemaire, Jonathan D. Turner, Danielle Perez-Bercoff
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Biomedicines
Subjects:
<i>TERT</i> promoter mutations
Telomerase
TERT
<i>TERT</i> transcription
bidirectional promoter
lncRNA <i>TAPAS</i>
Online Access:https://www.mdpi.com/2227-9059/9/12/1773

Internet

https://www.mdpi.com/2227-9059/9/12/1773

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