HIV-1 drug resistance in adults and adolescents on protease inhibitor-based antiretroviral therapy in KwaZulu-Natal Province, South Africa

HIV-1 drug resistance in adults and adolescents on protease inhibitor-based antiretroviral therapy in KwaZulu-Natal Province, South Africa

ABSTRACT: Objectives: In low–middle-income countries, increasing levels of HIV drug resistance (HIVDR) on second-line protease inhibitor (PI)-based regimens are a cause for concern given the limited drug options for third-line antiretroviral therapy (ART). We conducted a retrospective analysis of r...

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Bibliographic Details
Main Authors: Benjamin Chimukangara, Richard J. Lessells, Benn Sartorius, Lilishia Gounder, Sontaga Manyana, Melendhran Pillay, Lavanya Singh, Jennifer Giandhari, Kerusha Govender, Reshmi Samuel, Nokukhanya Msomi, Kogieleum Naidoo, Tulio de Oliveira, Pravi Moodley, Raveen Parboosing
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
HIV-1
Adults and adolescents
Protease inhibitor
Drug resistance
Antiretroviral therapy
Third-line ART
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716521002496

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