Time estimation and arousal responses in dopa-responsive dystonia

Time estimation and arousal responses in dopa-responsive dystonia

Abstract Dopa-responsive dystonia (DRD) is caused by an impaired dopamine biosynthesis due to a GTP-cyclohydrolase-1 (GCH1) deficiency, resulting in a combination of dystonia and parkinsonism. However, the effect of GCH1 mutations and levodopa treatment on motor control beyond simple movements, such...

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Bibliographic Details
Main Authors:	Leonie F. Becker, Sinem Tunc, Peter Murphy, Tobias Bäumer, Anne Weissbach, Martje G. Pauly, Duha M. Al-Shorafat, Gerard Saranza, Anthony E. Lang, Christian Beste, Tobias H. Donner, Julius Verrel, Alexander Münchau
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-08-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-022-17545-w

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