Inverse Relation between MxA Gene Expression and Age in Multiple Sclerosis Patients Reveals a Gender Difference in Response to Interferon Therapy

Inverse Relation between MxA Gene Expression and Age in Multiple Sclerosis Patients Reveals a Gender Difference in Response to Interferon Therapy

Multiple sclerosis (MS) is an inflammatory, multifocal, immune-mediated disease of the central nervous system that women are at a higher risk to acquire than men. Myxovirus resistance protein A (MxA) is used as a predictive marker of bioactivity of interferon-beta (IFN-β) therapy in MS patients. Thi...

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Bibliographic Details
Main Authors: Mohammad Taheri, Mohammadreza Mirinezhad, Mir Davood Omrani, Elham Sajjadi, Hidetoshi Inoko, Arezou Sayad
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2017-02-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Gene expression
Interferon-beta
Multiple sclerosis
Mx1
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/859

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