Prophylactic and Therapeutic Effects of MOG-Conjugated PLGA Nanoparticles in C57Bl/6 Mouse Model of Multiple Sclerosis

Prophylactic and Therapeutic Effects of MOG-Conjugated PLGA Nanoparticles in C57Bl/6 Mouse Model of Multiple Sclerosis

Purpose: Multiple sclerosis (MS) is a debilitating neuroinflammatory disorder of the central nervous system. It is believed to result from an impaired immune response against myelin components especially myelin oligodendrocyte glycoprotein (MOG). Some efforts have been made to bioconjugate the MOG p...

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Bibliographic Details
Main Authors:	Mehrdad Gholamzad, Hussein Baharlooi, Mehdi Shafiee Ardestani, Zeinab Seyedkhan, Maryam Azimi
Format:	Article
Language:	English
Published:	Tabriz University of Medical Sciences 2021-06-01
Series:	Advanced Pharmaceutical Bulletin
Subjects:	multiple sclerosis experimental autoimmune encephalomyelitis myelin oligodendrocyte glycoprotein poly (lactic-co-glycolic acid) regulatory t cell immune tolerance biomaterials
Online Access:	https://apb.tbzmed.ac.ir/PDF/apb-11-505.pdf

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