KLK4 Induces Anti-Tumor Effects in Human Xenograft Mouse Models of Orthotopic and Metastatic Prostate Cancer

KLK4 Induces Anti-Tumor Effects in Human Xenograft Mouse Models of Orthotopic and Metastatic Prostate Cancer

Recent reports have suggested the role of kallikrein-related peptidase 4 (KLK4) to be that of remodeling the tumor microenvironment in many cancers, including prostate cancer. Notably, these studies have suggested a pro-tumorigenic role for KLK4, especially in prostate cancer. However, these have be...

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Bibliographic Details
Main Authors: Brian W.-C. Tse, Thomas Kryza, Mei-Chun Yeh, Ying Dong, Kamil A. Sokolowski, Carina Walpole, Tobias Dreyer, Johanna Felber, Jonathan Harris, Viktor Magdolen, Pamela J. Russell, Judith A. Clements
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
kallikrein-related peptidase 4
KLK4
prostate cancer
metastasis
tumor xenografts
imaging
Online Access:https://www.mdpi.com/2072-6694/12/12/3501

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