A randomised controlled trial of the probiotic Bifidobacterium breve BBG-001 in preterm babies to prevent sepsis, necrotising enterocolitis and death: the Probiotics in Preterm infantS (PiPS) trial

A randomised controlled trial of the probiotic Bifidobacterium breve BBG-001 in preterm babies to prevent sepsis, necrotising enterocolitis and death: the Probiotics in Preterm infantS (PiPS) trial

Background: Necrotising enterocolitis (NEC) and late-onset sepsis remain important causes of death and morbidity in preterm babies. Probiotic administration might strengthen intestinal barrier function and provide protection; this is supported by published meta-analyses, but there is a lack of large...

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Bibliographic Details
Main Authors: Kate Costeloe, Ursula Bowler, Peter Brocklehurst, Pollyanna Hardy, Paul Heal, Edmund Juszczak, Andy King, Nicola Panton, Fiona Stacey, Angela Whiley, Mark Wilks, Michael R Millar
Format: Article
Language:English
Published: NIHR Journals Library 2016-08-01
Series:Health Technology Assessment
Subjects:
preterm
preterm infant
necrotising enterocolitis
sepsis
perinatal mortality
probiotic
randomised controlled trial
Online Access:https://doi.org/10.3310/hta20660

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