Repeated measures of Heparin-binding protein (HBP) and procalcitonin during septic shock: biomarker kinetics and association with cardiovascular organ dysfunction

Repeated measures of Heparin-binding protein (HBP) and procalcitonin during septic shock: biomarker kinetics and association with cardiovascular organ dysfunction

Abstract Background Heparin-binding protein (HBP) is a neutrophil-derived pro-inflammatory protein, an inducer of endothelial dysfunction and vascular permeability and a promising prognostic biomarker in sepsis. This exploratory study aims to describe the kinetics of plasma HBP during septic shock a...

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Bibliographic Details
Main Authors: Jonas Tverring, Niklas Nielsen, Josef Dankiewicz, Adam Linder, Fredrik Kahn, Per Åkesson
Format: Article
Language:English
Published: SpringerOpen 2020-09-01
Series:Intensive Care Medicine Experimental
Subjects:
Heparin-binding protein
Procalcitonin
Repeated measures
Kinetics
Sepsis
Septic shock
Online Access:http://link.springer.com/article/10.1186/s40635-020-00338-8

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