Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: Biomechanical and biocorrosion perspectives
Biodegradable metals (BMs) gradually degrade in vivo by releasing corrosion products once exposed to the physiological environment in the body. Complete dissolution of biodegradable implants assists tissue healing, with no implant residues in the surrounding tissues. In recent years, three classes o...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2021-03-01
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| Series: | Bioactive Materials |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X20302334 |
| _version_ | 1797204092890644480 |
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| author | Humayun Kabir Khurram Munir Cuie Wen Yuncang Li |
| author_facet | Humayun Kabir Khurram Munir Cuie Wen Yuncang Li |
| author_sort | Humayun Kabir |
| collection | DOAJ |
| description | Biodegradable metals (BMs) gradually degrade in vivo by releasing corrosion products once exposed to the physiological environment in the body. Complete dissolution of biodegradable implants assists tissue healing, with no implant residues in the surrounding tissues. In recent years, three classes of BMs have been extensively investigated, including magnesium (Mg)-based, iron (Fe)-based, and zinc (Zn)-based BMs. Among these three BMs, Mg-based materials have undergone the most clinical trials. However, Mg-based BMs generally exhibit faster degradation rates, which may not match the healing periods for bone tissue, whereas Fe-based BMs exhibit slower and less complete in vivo degradation. Zn-based BMs are now considered a new class of BMs due to their intermediate degradation rates, which fall between those of Mg-based BMs and Fe-based BMs, thus requiring extensive research to validate their suitability for biomedical applications. In the present study, recent research and development on Zn-based BMs are reviewed in conjunction with discussion of their advantages and limitations in relation to existing BMs. The underlying roles of alloy composition, microstructure, and processing technique on the mechanical and corrosion properties of Zn-based BMs are also discussed. |
| first_indexed | 2024-04-24T08:29:44Z |
| format | Article |
| id | doaj.art-06d8a9fa70c64e65a9cc5b7d04361f28 |
| institution | Directory Open Access Journal |
| issn | 2452-199X |
| language | English |
| last_indexed | 2024-04-24T08:29:44Z |
| publishDate | 2021-03-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Bioactive Materials |
| spelling | doaj.art-06d8a9fa70c64e65a9cc5b7d04361f282024-04-16T20:22:57ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2021-03-0163836879Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: Biomechanical and biocorrosion perspectivesHumayun Kabir0Khurram Munir1Cuie Wen2Yuncang Li3School of Engineering, RMIT University, Melbourne, Victoria, 3001, AustraliaSchool of Engineering, RMIT University, Melbourne, Victoria, 3001, AustraliaSchool of Engineering, RMIT University, Melbourne, Victoria, 3001, AustraliaCorresponding author.; School of Engineering, RMIT University, Melbourne, Victoria, 3001, AustraliaBiodegradable metals (BMs) gradually degrade in vivo by releasing corrosion products once exposed to the physiological environment in the body. Complete dissolution of biodegradable implants assists tissue healing, with no implant residues in the surrounding tissues. In recent years, three classes of BMs have been extensively investigated, including magnesium (Mg)-based, iron (Fe)-based, and zinc (Zn)-based BMs. Among these three BMs, Mg-based materials have undergone the most clinical trials. However, Mg-based BMs generally exhibit faster degradation rates, which may not match the healing periods for bone tissue, whereas Fe-based BMs exhibit slower and less complete in vivo degradation. Zn-based BMs are now considered a new class of BMs due to their intermediate degradation rates, which fall between those of Mg-based BMs and Fe-based BMs, thus requiring extensive research to validate their suitability for biomedical applications. In the present study, recent research and development on Zn-based BMs are reviewed in conjunction with discussion of their advantages and limitations in relation to existing BMs. The underlying roles of alloy composition, microstructure, and processing technique on the mechanical and corrosion properties of Zn-based BMs are also discussed.http://www.sciencedirect.com/science/article/pii/S2452199X20302334BiocorrosionBiodegradable metalsTissue engineeringZinc-based alloys and composites |
| spellingShingle | Humayun Kabir Khurram Munir Cuie Wen Yuncang Li Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: Biomechanical and biocorrosion perspectives Bioactive Materials Biocorrosion Biodegradable metals Tissue engineering Zinc-based alloys and composites |
| title | Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: Biomechanical and biocorrosion perspectives |
| title_full | Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: Biomechanical and biocorrosion perspectives |
| title_fullStr | Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: Biomechanical and biocorrosion perspectives |
| title_full_unstemmed | Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: Biomechanical and biocorrosion perspectives |
| title_short | Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: Biomechanical and biocorrosion perspectives |
| title_sort | recent research and progress of biodegradable zinc alloys and composites for biomedical applications biomechanical and biocorrosion perspectives |
| topic | Biocorrosion Biodegradable metals Tissue engineering Zinc-based alloys and composites |
| url | http://www.sciencedirect.com/science/article/pii/S2452199X20302334 |
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