Paths to the discovery of antivenom serotherapy in France

Abstract The current study presents a descriptive chronological survey of the articles published by Césaire Auguste Phisalix and Albert Calmette on snake poison, with the aim of shedding a light on the areas of research and reasoning followed by these scientists, leading up to their simultaneous dis...

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Main Author: Rosany Bochner
Format: Article
Language:English
Published: SciELO 2016-07-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100201&lng=en&tlng=en
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author Rosany Bochner
author_facet Rosany Bochner
author_sort Rosany Bochner
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description Abstract The current study presents a descriptive chronological survey of the articles published by Césaire Auguste Phisalix and Albert Calmette on snake poison, with the aim of shedding a light on the areas of research and reasoning followed by these scientists, leading up to their simultaneous discovery of antivenom serotherapy in 1894. The path taken by Phisalix is revealed in 15 articles that demonstrate the motivation of a naturalist and the way he confronted the puzzle of immunity against snake venom. In the case of Calmette, two articles preceded the discovery; microbiology was his theoretical base and the Pasteurian spirit of solving health problems his driving force. These two researchers followed distinct paths, mobilized by different motivations, but produced one single result. It is incontestable that the discovery of antivenom serotherapy was the work of two groups of researchers who deserve equal recognition, but who, in fact, did not receive it. Following the discovery both Calmette and Phisalix returned to their previous motivations. Calmette put the discovery into practice and began to produce antivenom serum in Lille. He came to be generally considered as the sole discoverer of antivenom serotherapy and was the recipient of a number of prestigious prizes. Phisalix, on the other hand, received little recognition and returned to his original interests, devoting himself to research on natural immunity. In Brazil, the discovery of antivenom serum therapy had a profound impact on the work of Vital Brazil Mineiro da Campanha, a researcher known worldwide for his scientific discoveries and for the evidence of the specificity of antivenom serums.
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spelling doaj.art-06da0fbd63f34d50bcf5b2469f0f01aa2022-12-21T17:57:29ZengSciELOJournal of Venomous Animals and Toxins including Tropical Diseases1678-91992016-07-0122010.1186/s40409-016-0074-7S1678-91992016000100201Paths to the discovery of antivenom serotherapy in FranceRosany BochnerAbstract The current study presents a descriptive chronological survey of the articles published by Césaire Auguste Phisalix and Albert Calmette on snake poison, with the aim of shedding a light on the areas of research and reasoning followed by these scientists, leading up to their simultaneous discovery of antivenom serotherapy in 1894. The path taken by Phisalix is revealed in 15 articles that demonstrate the motivation of a naturalist and the way he confronted the puzzle of immunity against snake venom. In the case of Calmette, two articles preceded the discovery; microbiology was his theoretical base and the Pasteurian spirit of solving health problems his driving force. These two researchers followed distinct paths, mobilized by different motivations, but produced one single result. It is incontestable that the discovery of antivenom serotherapy was the work of two groups of researchers who deserve equal recognition, but who, in fact, did not receive it. Following the discovery both Calmette and Phisalix returned to their previous motivations. Calmette put the discovery into practice and began to produce antivenom serum in Lille. He came to be generally considered as the sole discoverer of antivenom serotherapy and was the recipient of a number of prestigious prizes. Phisalix, on the other hand, received little recognition and returned to his original interests, devoting himself to research on natural immunity. In Brazil, the discovery of antivenom serum therapy had a profound impact on the work of Vital Brazil Mineiro da Campanha, a researcher known worldwide for his scientific discoveries and for the evidence of the specificity of antivenom serums.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100201&lng=en&tlng=enCalmettePhisalixAntivenom serotherapySnakeHistory of science
spellingShingle Rosany Bochner
Paths to the discovery of antivenom serotherapy in France
Journal of Venomous Animals and Toxins including Tropical Diseases
Calmette
Phisalix
Antivenom serotherapy
Snake
History of science
title Paths to the discovery of antivenom serotherapy in France
title_full Paths to the discovery of antivenom serotherapy in France
title_fullStr Paths to the discovery of antivenom serotherapy in France
title_full_unstemmed Paths to the discovery of antivenom serotherapy in France
title_short Paths to the discovery of antivenom serotherapy in France
title_sort paths to the discovery of antivenom serotherapy in france
topic Calmette
Phisalix
Antivenom serotherapy
Snake
History of science
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100201&lng=en&tlng=en
work_keys_str_mv AT rosanybochner pathstothediscoveryofantivenomserotherapyinfrance