Short-term effects of positive expiratory airway pressure in patients being weaned from mechanical ventilation
OBJECTIVE: To investigate the feasibility and the cardiorespiratory effects of using positive expiratory airway pressure, a physiotherapeutic tool, in comparison with a T-tube, to wean patients from mechanical ventilation. METHODS/DESIGN: A prospective, randomized, cross-over study. SETTING: Two int...
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| Format: | Article |
| Language: | English |
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Elsevier España
2009-05-01
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| Series: | Clinics |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322009000500006 |
| _version_ | 1828295931571732480 |
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| author | Marcelo de Mello Rieder Alexandre Doval da Costa Silvia Regina Rios Vieira |
| author_facet | Marcelo de Mello Rieder Alexandre Doval da Costa Silvia Regina Rios Vieira |
| author_sort | Marcelo de Mello Rieder |
| collection | DOAJ |
| description | OBJECTIVE: To investigate the feasibility and the cardiorespiratory effects of using positive expiratory airway pressure, a physiotherapeutic tool, in comparison with a T-tube, to wean patients from mechanical ventilation. METHODS/DESIGN: A prospective, randomized, cross-over study. SETTING: Two intensive care units. PATIENTS AND INTERVENTIONS: We evaluated forty patients who met weaning criteria and had been mechanically-ventilated for more than 48 hours, mean age 59 years, including 23 males. All patients were submitted to the T-tube and Expiratory Positive Airway Pressure devices, at 7 cm H2O, during a 30-minute period. Cardiorespiratory variables including work of breathing, respiratory rate (rr), peripheral oxygen saturation (SpO2), heart rate (hr), systolic, diastolic and mean arterial pressures (SAP, DAP, MAP) were measured in the first and thirtieth minutes. The condition was analyzed as an entire sample set (n=40) and was also divided into subconditions: chronic obstructive pulmonary disease (n=14) and non-chronic obstructive pulmonary disease (non- chronic obstructive pulmonary disease) (n=26) categories. Comparisons were made using a t-test and Analysis of Variance. The level of significance was p < 0.05. RESULTS: Our data showed an increase in work of breathing in the first and thirtieth minutes in the EPAP condition (0.86+ 0.43 and 1.02+1.3) as compared with the T-tube condition (0.25+0.26 and 0.26+0.35) (p<0.05), verified by the flow-sensor monitor (values in J/L). No statistical differences were observed when comparing the Expiratory Positive Airway Pressure and T-tube conditions with regard to cardiorespiratory measurements. The same result was observed for both chronic obstructive pulmonary disease and non- chronic obstructive pulmonary disease subconditions. CONCLUSIONS: Our study demonstrated that, in weaning patients from mechanical ventilation, the use of a fixed level of Expiratory Positive Airway Pressure caused an increase in work of breathing that was not accompanied by any other significant cardiorespiratory changes. Therefore, we have to be cautious when using Expiratory Positive Airway Pressure as a physiotherapeutic tool during weaning from mechanical ventilation. |
| first_indexed | 2024-04-13T12:04:30Z |
| format | Article |
| id | doaj.art-06dd57216eda49bbb6dff338195aa186 |
| institution | Directory Open Access Journal |
| issn | 1807-5932 1980-5322 |
| language | English |
| last_indexed | 2024-04-13T12:04:30Z |
| publishDate | 2009-05-01 |
| publisher | Elsevier España |
| record_format | Article |
| series | Clinics |
| spelling | doaj.art-06dd57216eda49bbb6dff338195aa1862022-12-22T02:47:41ZengElsevier EspañaClinics1807-59321980-53222009-05-0164540340810.1590/S1807-59322009000500006Short-term effects of positive expiratory airway pressure in patients being weaned from mechanical ventilationMarcelo de Mello RiederAlexandre Doval da CostaSilvia Regina Rios VieiraOBJECTIVE: To investigate the feasibility and the cardiorespiratory effects of using positive expiratory airway pressure, a physiotherapeutic tool, in comparison with a T-tube, to wean patients from mechanical ventilation. METHODS/DESIGN: A prospective, randomized, cross-over study. SETTING: Two intensive care units. PATIENTS AND INTERVENTIONS: We evaluated forty patients who met weaning criteria and had been mechanically-ventilated for more than 48 hours, mean age 59 years, including 23 males. All patients were submitted to the T-tube and Expiratory Positive Airway Pressure devices, at 7 cm H2O, during a 30-minute period. Cardiorespiratory variables including work of breathing, respiratory rate (rr), peripheral oxygen saturation (SpO2), heart rate (hr), systolic, diastolic and mean arterial pressures (SAP, DAP, MAP) were measured in the first and thirtieth minutes. The condition was analyzed as an entire sample set (n=40) and was also divided into subconditions: chronic obstructive pulmonary disease (n=14) and non-chronic obstructive pulmonary disease (non- chronic obstructive pulmonary disease) (n=26) categories. Comparisons were made using a t-test and Analysis of Variance. The level of significance was p < 0.05. RESULTS: Our data showed an increase in work of breathing in the first and thirtieth minutes in the EPAP condition (0.86+ 0.43 and 1.02+1.3) as compared with the T-tube condition (0.25+0.26 and 0.26+0.35) (p<0.05), verified by the flow-sensor monitor (values in J/L). No statistical differences were observed when comparing the Expiratory Positive Airway Pressure and T-tube conditions with regard to cardiorespiratory measurements. The same result was observed for both chronic obstructive pulmonary disease and non- chronic obstructive pulmonary disease subconditions. CONCLUSIONS: Our study demonstrated that, in weaning patients from mechanical ventilation, the use of a fixed level of Expiratory Positive Airway Pressure caused an increase in work of breathing that was not accompanied by any other significant cardiorespiratory changes. Therefore, we have to be cautious when using Expiratory Positive Airway Pressure as a physiotherapeutic tool during weaning from mechanical ventilation.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322009000500006Positive Expiratory Airway PressureWeaningMechanical VentilationIntensive Care UnitPhysiotherapy |
| spellingShingle | Marcelo de Mello Rieder Alexandre Doval da Costa Silvia Regina Rios Vieira Short-term effects of positive expiratory airway pressure in patients being weaned from mechanical ventilation Clinics Positive Expiratory Airway Pressure Weaning Mechanical Ventilation Intensive Care Unit Physiotherapy |
| title | Short-term effects of positive expiratory airway pressure in patients being weaned from mechanical ventilation |
| title_full | Short-term effects of positive expiratory airway pressure in patients being weaned from mechanical ventilation |
| title_fullStr | Short-term effects of positive expiratory airway pressure in patients being weaned from mechanical ventilation |
| title_full_unstemmed | Short-term effects of positive expiratory airway pressure in patients being weaned from mechanical ventilation |
| title_short | Short-term effects of positive expiratory airway pressure in patients being weaned from mechanical ventilation |
| title_sort | short term effects of positive expiratory airway pressure in patients being weaned from mechanical ventilation |
| topic | Positive Expiratory Airway Pressure Weaning Mechanical Ventilation Intensive Care Unit Physiotherapy |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322009000500006 |
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