Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells
Innate-like T cells such as invariant natural killer T (iNKT) and mucosal-associated invariant T (MAIT) cells both develop in the thymus. Here the authors use single-cell RNA sequencing to show that mouse iNKT and MAIT share components of developmental regulation, with a transcription factor, Hivep3...
Main Authors: | S. Harsha Krovi, Jingjing Zhang, Mary Jessamine Michaels-Foster, Tonya Brunetti, Liyen Loh, James Scott-Browne, Laurent Gapin |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-20073-8 |
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