Therapeutic efficiency of human amniotic epithelial stem cell-derived functional hepatocyte-like cells in mice with acute hepatic failure

Therapeutic efficiency of human amniotic epithelial stem cell-derived functional hepatocyte-like cells in mice with acute hepatic failure

Abstract Background Hepatocyte transplantation has been proposed as an effective treatment for patients with acute liver failure (ALF), but its application is limited by a severe shortage of donor livers. Human pluripotent stem cells (hPSCs) have emerged as a potential cell source for regenerative m...

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Bibliographic Details
Main Authors: Quan-Wen Liu, Qian-Yu Liu, Jing-Yuan Li, Li Wei, Kang-Kang Ren, Xiang-Cheng Zhang, Ting Ding, Ling Xiao, Wen-Jie Zhang, Han-You Wu, Hong-Bo Xin
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Stem Cell Research & Therapy
Subjects:
Acute liver failure
Human amniotic epithelial stem cells
Hepatocyte-like cells
Human primary hepatocytes
Cell transplantation
Online Access:http://link.springer.com/article/10.1186/s13287-018-1063-2

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