Parvalbumin affects skeletal muscle trophism through modulation of mitochondrial calcium uptake

Parvalbumin affects skeletal muscle trophism through modulation of mitochondrial calcium uptake

Summary: Parvalbumin (PV) is a cytosolic Ca2+-binding protein highly expressed in fast skeletal muscle, contributing to an increased relaxation rate. Moreover, PV is an “atrogene” downregulated in most muscle atrophy conditions. Here, we exploit mice lacking PV to explore the link between the two PV...

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Bibliographic Details
Main Authors: Gaia Butera, Denis Vecellio Reane, Marta Canato, Laura Pietrangelo, Simona Boncompagni, Feliciano Protasi, Rosario Rizzuto, Carlo Reggiani, Anna Raffaello
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Cell Reports
Subjects:
calcium buffer
mitochondria
skeletal muscle
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721004204

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