B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine
In this study, we present the ultrasound imaging features of lymph nodes arising in the regional lymph node chain after the first or second dose of the Pfizer-BioNTech COVID-19 vaccine. Ipsilateral lymphadenopathy adjacent to the vaccine injection site is an extremely rare but expected adverse react...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Cukurova University
2022-06-01
|
Series: | Cukurova Medical Journal |
Subjects: | |
Online Access: | https://dergipark.org.tr/tr/download/article-file/2318560 |
_version_ | 1797919828404600832 |
---|---|
author | Alper Dilli Aynur Turan Veysel Kaplanoğlu Hatice Kaplanoğlu |
author_facet | Alper Dilli Aynur Turan Veysel Kaplanoğlu Hatice Kaplanoğlu |
author_sort | Alper Dilli |
collection | DOAJ |
description | In this study, we present the ultrasound imaging features of lymph nodes arising in the regional lymph node chain after the first or second dose of the Pfizer-BioNTech COVID-19 vaccine. Ipsilateral lymphadenopathy adjacent to the vaccine injection site is an extremely rare but expected adverse reaction following COVID-19 vaccination. Although axillary lymphadenopathy is more common, cases of supraclavicular lymphadenopathy have also been reported after widespread vaccination against COVID-19. Ultrasonography examinations were performed on seven patients with no previous pathological conditions, who presented to our radiology department after receiving the Pfizer-BioNTech COVID-19 vaccine. Bilateral axillary, supraclavicular and subclavicular lymph node stations were explored. These patients typically present with enlarged hypoechoic lymph nodes with the loss of fatty hilum, asymmetric or diffuse cortical thickening, and increased hilar and cortical vascularization on the color doppler ultrasonography of the ipsilateral axillary and supraclavicular regions. Radiologists and clinicians should be aware of the ultrasonographic features of these lymph nodes and should inform the patient that these lymph nodes are often a self-limiting process. Thus, unnecessary axillary lymph node biopsies should be avoided, and patients should be treated conservatively. |
first_indexed | 2024-04-10T13:52:47Z |
format | Article |
id | doaj.art-06e56c2a8d3d446e98bf60a779a125d8 |
institution | Directory Open Access Journal |
issn | 2602-3040 |
language | English |
last_indexed | 2024-04-10T13:52:47Z |
publishDate | 2022-06-01 |
publisher | Cukurova University |
record_format | Article |
series | Cukurova Medical Journal |
spelling | doaj.art-06e56c2a8d3d446e98bf60a779a125d82023-02-15T16:10:38ZengCukurova UniversityCukurova Medical Journal2602-30402022-06-0147289189710.17826/cumj.108999548B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccineAlper Dilli0Aynur Turan1Veysel Kaplanoğlu2Hatice Kaplanoğlu3Sağlık Bilimleri Üniversitesi Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Patoloji Bölümü, Ankara, TurkiyeSağlık Bilimleri Üniversitesi Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Patoloji Bölümü, Ankara, TurkiyeSağlık Bilimleri Üniversitesi Keçiören Eğitim ve Araştırma Hastanesi, Patoloji Bölümü, Ankara, TurkiyeSağlık Bilimleri Üniversitesi Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Radyoloji Bölümü, Ankara, TurkiyeIn this study, we present the ultrasound imaging features of lymph nodes arising in the regional lymph node chain after the first or second dose of the Pfizer-BioNTech COVID-19 vaccine. Ipsilateral lymphadenopathy adjacent to the vaccine injection site is an extremely rare but expected adverse reaction following COVID-19 vaccination. Although axillary lymphadenopathy is more common, cases of supraclavicular lymphadenopathy have also been reported after widespread vaccination against COVID-19. Ultrasonography examinations were performed on seven patients with no previous pathological conditions, who presented to our radiology department after receiving the Pfizer-BioNTech COVID-19 vaccine. Bilateral axillary, supraclavicular and subclavicular lymph node stations were explored. These patients typically present with enlarged hypoechoic lymph nodes with the loss of fatty hilum, asymmetric or diffuse cortical thickening, and increased hilar and cortical vascularization on the color doppler ultrasonography of the ipsilateral axillary and supraclavicular regions. Radiologists and clinicians should be aware of the ultrasonographic features of these lymph nodes and should inform the patient that these lymph nodes are often a self-limiting process. Thus, unnecessary axillary lymph node biopsies should be avoided, and patients should be treated conservatively.https://dergipark.org.tr/tr/download/article-file/2318560covid-19mrna vaccinesupraclavicularlymphadenopathyultrasonographycovid-19mrna aşısısupraklavikülerlenfadenopatiultrasonografi |
spellingShingle | Alper Dilli Aynur Turan Veysel Kaplanoğlu Hatice Kaplanoğlu B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine Cukurova Medical Journal covid-19 mrna vaccine supraclavicular lymphadenopathy ultrasonography covid-19 mrna aşısı supraklaviküler lenfadenopati ultrasonografi |
title | B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine |
title_full | B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine |
title_fullStr | B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine |
title_full_unstemmed | B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine |
title_short | B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine |
title_sort | b mode and doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mrna covid 19 vaccine |
topic | covid-19 mrna vaccine supraclavicular lymphadenopathy ultrasonography covid-19 mrna aşısı supraklaviküler lenfadenopati ultrasonografi |
url | https://dergipark.org.tr/tr/download/article-file/2318560 |
work_keys_str_mv | AT alperdilli bmodeanddopplerultrasonographypatternsofaxillaryandsupraclavicularlymphadenopathyassociatedwithmrnacovid19vaccine AT aynurturan bmodeanddopplerultrasonographypatternsofaxillaryandsupraclavicularlymphadenopathyassociatedwithmrnacovid19vaccine AT veyselkaplanoglu bmodeanddopplerultrasonographypatternsofaxillaryandsupraclavicularlymphadenopathyassociatedwithmrnacovid19vaccine AT haticekaplanoglu bmodeanddopplerultrasonographypatternsofaxillaryandsupraclavicularlymphadenopathyassociatedwithmrnacovid19vaccine |