B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine

In this study, we present the ultrasound imaging features of lymph nodes arising in the regional lymph node chain after the first or second dose of the Pfizer-BioNTech COVID-19 vaccine. Ipsilateral lymphadenopathy adjacent to the vaccine injection site is an extremely rare but expected adverse react...

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Main Authors: Alper Dilli, Aynur Turan, Veysel Kaplanoğlu, Hatice Kaplanoğlu
Format: Article
Language:English
Published: Cukurova University 2022-06-01
Series:Cukurova Medical Journal
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/2318560
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author Alper Dilli
Aynur Turan
Veysel Kaplanoğlu
Hatice Kaplanoğlu
author_facet Alper Dilli
Aynur Turan
Veysel Kaplanoğlu
Hatice Kaplanoğlu
author_sort Alper Dilli
collection DOAJ
description In this study, we present the ultrasound imaging features of lymph nodes arising in the regional lymph node chain after the first or second dose of the Pfizer-BioNTech COVID-19 vaccine. Ipsilateral lymphadenopathy adjacent to the vaccine injection site is an extremely rare but expected adverse reaction following COVID-19 vaccination. Although axillary lymphadenopathy is more common, cases of supraclavicular lymphadenopathy have also been reported after widespread vaccination against COVID-19. Ultrasonography examinations were performed on seven patients with no previous pathological conditions, who presented to our radiology department after receiving the Pfizer-BioNTech COVID-19 vaccine. Bilateral axillary, supraclavicular and subclavicular lymph node stations were explored. These patients typically present with enlarged hypoechoic lymph nodes with the loss of fatty hilum, asymmetric or diffuse cortical thickening, and increased hilar and cortical vascularization on the color doppler ultrasonography of the ipsilateral axillary and supraclavicular regions. Radiologists and clinicians should be aware of the ultrasonographic features of these lymph nodes and should inform the patient that these lymph nodes are often a self-limiting process. Thus, unnecessary axillary lymph node biopsies should be avoided, and patients should be treated conservatively.
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spelling doaj.art-06e56c2a8d3d446e98bf60a779a125d82023-02-15T16:10:38ZengCukurova UniversityCukurova Medical Journal2602-30402022-06-0147289189710.17826/cumj.108999548B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccineAlper Dilli0Aynur Turan1Veysel Kaplanoğlu2Hatice Kaplanoğlu3Sağlık Bilimleri Üniversitesi Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Patoloji Bölümü, Ankara, TurkiyeSağlık Bilimleri Üniversitesi Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Patoloji Bölümü, Ankara, TurkiyeSağlık Bilimleri Üniversitesi Keçiören Eğitim ve Araştırma Hastanesi, Patoloji Bölümü, Ankara, TurkiyeSağlık Bilimleri Üniversitesi Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Radyoloji Bölümü, Ankara, TurkiyeIn this study, we present the ultrasound imaging features of lymph nodes arising in the regional lymph node chain after the first or second dose of the Pfizer-BioNTech COVID-19 vaccine. Ipsilateral lymphadenopathy adjacent to the vaccine injection site is an extremely rare but expected adverse reaction following COVID-19 vaccination. Although axillary lymphadenopathy is more common, cases of supraclavicular lymphadenopathy have also been reported after widespread vaccination against COVID-19. Ultrasonography examinations were performed on seven patients with no previous pathological conditions, who presented to our radiology department after receiving the Pfizer-BioNTech COVID-19 vaccine. Bilateral axillary, supraclavicular and subclavicular lymph node stations were explored. These patients typically present with enlarged hypoechoic lymph nodes with the loss of fatty hilum, asymmetric or diffuse cortical thickening, and increased hilar and cortical vascularization on the color doppler ultrasonography of the ipsilateral axillary and supraclavicular regions. Radiologists and clinicians should be aware of the ultrasonographic features of these lymph nodes and should inform the patient that these lymph nodes are often a self-limiting process. Thus, unnecessary axillary lymph node biopsies should be avoided, and patients should be treated conservatively.https://dergipark.org.tr/tr/download/article-file/2318560covid-19mrna vaccinesupraclavicularlymphadenopathyultrasonographycovid-19mrna aşısısupraklavikülerlenfadenopatiultrasonografi
spellingShingle Alper Dilli
Aynur Turan
Veysel Kaplanoğlu
Hatice Kaplanoğlu
B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine
Cukurova Medical Journal
covid-19
mrna vaccine
supraclavicular
lymphadenopathy
ultrasonography
covid-19
mrna aşısı
supraklaviküler
lenfadenopati
ultrasonografi
title B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine
title_full B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine
title_fullStr B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine
title_full_unstemmed B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine
title_short B-mode and Doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mRNA COVID-19 vaccine
title_sort b mode and doppler ultrasonography patterns of axillary and supraclavicular lymphadenopathy associated with mrna covid 19 vaccine
topic covid-19
mrna vaccine
supraclavicular
lymphadenopathy
ultrasonography
covid-19
mrna aşısı
supraklaviküler
lenfadenopati
ultrasonografi
url https://dergipark.org.tr/tr/download/article-file/2318560
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AT veyselkaplanoglu bmodeanddopplerultrasonographypatternsofaxillaryandsupraclavicularlymphadenopathyassociatedwithmrnacovid19vaccine
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