Epidemiology of chronic kidney diseases in the Republic of Guinea; future dialysis needs
Background: Chronic kidney disease (CKD) is increasing worldwide and can lead to end-stage renal disease (ESRD). Objectives: Because few patients with ESRD in the Republic of Guinea have access to haemodialysis, we retrospectively evaluated the prevalence of CKD, ESRD and access to supportive therap...
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| Format: | Article |
| Language: | English |
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Society of Diabetic Nephropathy Prevention
2015-10-01
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| Series: | Journal of Nephropathology |
| Subjects: | |
| Online Access: | https://nephropathol.com/PDF/JNP-4-127.pdf |
| _version_ | 1797827954216009728 |
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| author | Alpha Oumar Bah Cisse Lamine Mamadou Cellou Balde Mamadou Lamine Yaya Bah Lionel Rostaing |
| author_facet | Alpha Oumar Bah Cisse Lamine Mamadou Cellou Balde Mamadou Lamine Yaya Bah Lionel Rostaing |
| author_sort | Alpha Oumar Bah |
| collection | DOAJ |
| description | Background: Chronic kidney disease (CKD) is increasing worldwide and can lead to end-stage renal disease (ESRD). Objectives: Because few patients with ESRD in the Republic of Guinea have access to haemodialysis, we retrospectively evaluated the prevalence of CKD, ESRD and access to supportive therapies. Patients and Methods: 579 CKD patients (304 males; mean age: 44 ± 16 years) were admitted into Conakry nephrology department, the only centre in the Republic of Guinea, between 2009 and 2013. Most patients (63%) resided within Conakry (the capital), 12.5% came from lower Guinea, 11.7% from middle Guinea, 7.9% from upper Guinea and 4.8% from forest Guinea. Results: Reasons for referral were increased serum creatinine (49.5%), hypertension (27%) and diffuse edema (17%). Also, 11% were diabetic, 12.5% were smokers, 17% were HIV-positive, 8.3% were HBV-positive and 15% were HCV-positive. The most frequent symptom at admission was nausea/vomiting (56%). Upon admission, 70.5% of patients already had ESRD. Although no kidney biopsies were performed it was assumed that 34% and 27% of patients had vascular nephropathy and chronic glomerulonephritis, respectively. Of the 385 ESRD patients, only 140 (36.3%) had access to haemodialysis (two sessions/week, 4 hours each). Most patients that received haemodialysis resided within the Conakry region (P < 0.0001). There were significant associations between mortality and (i) terminal stage of CKD (P = 0.0005), (ii) vascular nephropathy (P = 0.002), and (iii) nephropathies of unknown origin (P = 0.0001). Conclusions: A fourfold increase in haemodialysis machines is needed in Conakry, plus four new nephrology/haemodialysis centres within the Republic of Guinea, each holding ≥30 haemodialysis machines. |
| first_indexed | 2024-04-09T12:56:42Z |
| format | Article |
| id | doaj.art-06e5fd01ddb342bcb5b0072b5c3eb46d |
| institution | Directory Open Access Journal |
| issn | 2251-8363 2251-8819 |
| language | English |
| last_indexed | 2024-04-09T12:56:42Z |
| publishDate | 2015-10-01 |
| publisher | Society of Diabetic Nephropathy Prevention |
| record_format | Article |
| series | Journal of Nephropathology |
| spelling | doaj.art-06e5fd01ddb342bcb5b0072b5c3eb46d2023-05-13T11:34:00ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropathology2251-83632251-88192015-10-014412713310.12860/jnp.2015.24JNP_20151006210610Epidemiology of chronic kidney diseases in the Republic of Guinea; future dialysis needsAlpha Oumar Bah0Cisse Lamine1Mamadou Cellou Balde2Mamadou Lamine Yaya Bah3Lionel Rostaing4Nephrology Unit, Donka National Hospital, Conakry, Republic of GuineaNephrology Unit, Donka National Hospital, Conakry, Republic of GuineaNephrology Unit, Donka National Hospital, Conakry, Republic of GuineaNephrology Unit, Donka National Hospital, Conakry, Republic of GuineaDepartment of Nephrology and Organ Transplantation, CHU Rangueil, TSA 50032, Université Paul Sabatier, Toulouse, FranceBackground: Chronic kidney disease (CKD) is increasing worldwide and can lead to end-stage renal disease (ESRD). Objectives: Because few patients with ESRD in the Republic of Guinea have access to haemodialysis, we retrospectively evaluated the prevalence of CKD, ESRD and access to supportive therapies. Patients and Methods: 579 CKD patients (304 males; mean age: 44 ± 16 years) were admitted into Conakry nephrology department, the only centre in the Republic of Guinea, between 2009 and 2013. Most patients (63%) resided within Conakry (the capital), 12.5% came from lower Guinea, 11.7% from middle Guinea, 7.9% from upper Guinea and 4.8% from forest Guinea. Results: Reasons for referral were increased serum creatinine (49.5%), hypertension (27%) and diffuse edema (17%). Also, 11% were diabetic, 12.5% were smokers, 17% were HIV-positive, 8.3% were HBV-positive and 15% were HCV-positive. The most frequent symptom at admission was nausea/vomiting (56%). Upon admission, 70.5% of patients already had ESRD. Although no kidney biopsies were performed it was assumed that 34% and 27% of patients had vascular nephropathy and chronic glomerulonephritis, respectively. Of the 385 ESRD patients, only 140 (36.3%) had access to haemodialysis (two sessions/week, 4 hours each). Most patients that received haemodialysis resided within the Conakry region (P < 0.0001). There were significant associations between mortality and (i) terminal stage of CKD (P = 0.0005), (ii) vascular nephropathy (P = 0.002), and (iii) nephropathies of unknown origin (P = 0.0001). Conclusions: A fourfold increase in haemodialysis machines is needed in Conakry, plus four new nephrology/haemodialysis centres within the Republic of Guinea, each holding ≥30 haemodialysis machines.https://nephropathol.com/PDF/JNP-4-127.pdfchronic kidney diseasesend-stage renal diseasehemodialysis |
| spellingShingle | Alpha Oumar Bah Cisse Lamine Mamadou Cellou Balde Mamadou Lamine Yaya Bah Lionel Rostaing Epidemiology of chronic kidney diseases in the Republic of Guinea; future dialysis needs Journal of Nephropathology chronic kidney diseases end-stage renal disease hemodialysis |
| title | Epidemiology of chronic kidney diseases in the Republic of Guinea; future dialysis needs |
| title_full | Epidemiology of chronic kidney diseases in the Republic of Guinea; future dialysis needs |
| title_fullStr | Epidemiology of chronic kidney diseases in the Republic of Guinea; future dialysis needs |
| title_full_unstemmed | Epidemiology of chronic kidney diseases in the Republic of Guinea; future dialysis needs |
| title_short | Epidemiology of chronic kidney diseases in the Republic of Guinea; future dialysis needs |
| title_sort | epidemiology of chronic kidney diseases in the republic of guinea future dialysis needs |
| topic | chronic kidney diseases end-stage renal disease hemodialysis |
| url | https://nephropathol.com/PDF/JNP-4-127.pdf |
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