High Fat-High Fructose Diet Elicits Hypogonadotropism Culminating in Autophagy-Mediated Defective Differentiation of Ovarian Follicles

High Fat-High Fructose Diet Elicits Hypogonadotropism Culminating in Autophagy-Mediated Defective Differentiation of Ovarian Follicles

Pituitary gonadotropins directly govern ovarian functions, which are in turn regulated by the ovarian steroid hormones. The precise interplay of gonadotropins and steroid hormones is critical for follicle growth and differentiation. Furthermore, autophagy regulates ovarian follicle differentiation....

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Bibliographic Details
Main Authors: Chalikkaran Thilakan Rejani, Ajit Kumar Navin, Thekkey Madathil Valappil Mumthaz, Venugopal Bhuvarahamurthy
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
autophagy
GnRHR
hypogonadotropism hypogonadism
folliculogenesis
steroidogenesis
infertility
Online Access:https://www.mdpi.com/2073-4409/11/21/3447

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